U3750
Uridine
≥99%, synthetic (organic), powder
Synonyme(s) :
1-β-D-Ribofuranosyluracil, Uracil-1-β-D-ribofuranoside
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A propos de cet article
Formule empirique (notation de Hill) :
C9H12N2O6
Numéro CAS:
Poids moléculaire :
244.20
NACRES:
NA.51
PubChem Substance ID:
UNSPSC Code:
41106305
EC Number:
200-407-5
MDL number:
Beilstein/REAXYS Number:
754902
Assay:
≥99%
Biological source:
synthetic (organic)
Form:
powder
Solubility:
H2O: 50 mg/mL, clear, colorless
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Laissez-nous vous aiderNom du produit
Uridine, ≥99%
biological source
synthetic (organic)
Quality Level
assay
≥99%
form
powder
mp
163-167 °C (lit.)
solubility
H2O: 50 mg/mL, clear, colorless
SMILES string
OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=CC(=O)NC2=O
InChI
1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChI key
DRTQHJPVMGBUCF-XVFCMESISA-N
Gene Information
mouse ... Uck1(22245)
General description
Uridine is a uracil nucleoside, specific for RNA sequence. Uridine is present in blood, seminal fluid and cerebrospinal fluid. Uridine is synthesized in living organisms by de novo and salvage pathways.
Application
Uridine has been used:
- as a component of hippocampal neuron medium for culture of primary hippocampal neuron cells
- in uridine rescue experiments in mouse embryonic fibroblasts and human breast cancer cells
- in chase sequencing experiments
Biochem/physiol Actions
Uridine monophosphate is essential for protein glycosylation, polysaccharide biosynthesis and lipid metabolism. Oral administration of uridine is suggested for anisopoikilocytosis and epileptic encephalopathy disorders. Uridine has numerous biological functions like treating dry eye syndrome, regulating nervous system and favors reproduction. High levels of uridine are implicated in insulin resistance.
Classe de stockage
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Contenu apparenté
Product Information Sheet
PTEN regulates glutamine flux to pyrimidine synthesis and sensitivity to dihydroorotate dehydrogenase inhibition
Mathur D, et al.
Cancer Discovery, 7(4), 380390-380390 (2017)
Detection of phosphorylated Akt and MAPK in cell culture assays
Molgaard S, et al.
MethodsX, 3(2), 386398-386398 (2016)
Transient N-6-methyladenosine transcriptome sequencing reveals a regulatory role of m6A in splicing efficiency
Louloupi A, et al.
Cell Reports, 23(12), 34293437-34293437 (2018)