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Merck

PHR1273

Malic acid

Pharmaceutical Secondary Standard; Certified Reference Material

Synonyme(s) :

DL-Malic acid, (±)-2-Hydroxysuccinic acid, DL-Hydroxybutanedioic acid

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A propos de cet article

Formule linéaire :
HO2CCH2CH(OH)CO2H
Numéro CAS:
6915-15-7
Poids moléculaire :
134.09
NACRES:
NA.24
E Number:
E296
PubChem Substance ID:
329823269
UNSPSC Code:
41116107
EC Number:
230-022-8
MDL number:
MFCD00064212
Beilstein/REAXYS Number:
1723539

Principaux documents

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Nom du produit

Malic acid, Pharmaceutical Secondary Standard; Certified Reference Material

InChI key

BJEPYKJPYRNKOW-UHFFFAOYSA-N

InChI

1S/C4H6O5/c5-2(4(8)9)1-3(6)7/h2,5H,1H2,(H,6,7)(H,8,9)

SMILES string

OC(CC(O)=O)C(O)=O

grade

certified reference material
pharmaceutical secondary standard

agency

traceable to Ph. Eur. Y0000143
traceable to USP 1374601

vapor density

4.6 (vs air)

vapor pressure

<0.1 mmHg ( 20 °C)

API family

malic acid

CofA

current certificate can be downloaded

autoignition temp.

644 °F

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

mp

131-133 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care
pharmaceutical (small molecule)

format

neat

storage temp.

2-30°C

Quality Level

300

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Catégories apparentées

Analysis Note

These secondary standards offer multi-traceability to the US and EP primary standards, where they are available.

Application

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

General description

Malic acid is a naturally occurring acidulant and low acid food additive, present in most fruits and vegetables. It is widely used to enhance the flavor, adjust the pH value of alkaline products and to control the growth of bacteria.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Other Notes

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.
This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
To see an example of a Certificate of Analysis for this material enter LRAA0009 in the slot below. This is an example certificate only and may not be the lot that you receive.

wgk

WGK 1

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Classe de stockage

11 - Combustible Solids

flash_point_f

397.4 °F

flash_point_c

203 °C

Certificats d'analyse (COA)

Recherchez un Certificats d'analyse (COA) en saisissant le numéro de lot du produit. Les numéros de lot figurent sur l'étiquette du produit après les mots "Lot" ou "Batch".

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Consulter la Bibliothèque de documents

Fundamentals of Food Biotechnology (2014)
Prasanta Dey et al.
Biomolecules, 10(9) (2020-09-04)
Renal cell carcinoma has emerged as one of the leading causes of cancer-related deaths in the USA. Here, we examined the anticancer profile of oxindole derivatives (SH-859) in human renal cancer cells. Targeting 786-O cells by SH-859 inhibited cell growth
Hugo Oliveira et al.
PloS one, 9(10), e108376-e108376 (2014-10-08)
Resistance rates are increasing among several problematic Gram-negative pathogens, a fact that has encouraged the development of new antimicrobial agents. This paper characterizes a Salmonella phage endolysin (Lys68) and demonstrates its potential antimicrobial effectiveness when combined with organic acids towards
M Taillefer et al.
Applied and environmental microbiology, 81(7), 2423-2432 (2015-01-27)
Clostridium thermocellum produces ethanol as one of its major end products from direct fermentation of cellulosic biomass. Therefore, it is viewed as an attractive model for the production of biofuels via consolidated bioprocessing. However, a better understanding of the metabolic
Jie Chen et al.
BMC plant biology, 15, 28-28 (2015-02-04)
QTLs controlling individual sugars and acids (fructose, glucose, malic acid and tartaric acid) in grape berries have not yet been identified. The present study aimed to construct a high-density, high-quality genetic map of a winemaking grape cross with a complex
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