Register today!
Wednesday, May 22, 2019
M Lab™ Collaboration Center, Molsheim
You are invited to participate in Merck’s ADC & Bioconjugation Symposium. Learn, share and discuss today’s advancements with your peers and subject matter experts of the industry.
This one-day event will include:
Agenda*
Wednesday, May 22, 2019
| 9:30 - 10:00 | Registration and morning coffee |
| 10:00 - 10:05 | Welcome |
| Robert Guagliardo, Merck | |
| 10:05 - 10:20 | Opening remarks from the symposium chair |
| Dr. Vincent Turula, Pfizer | |
| Latest advances in drug development and linker-payload technologies | |
| 10:20 - 10:50 | Site-specific and stoichiometric functionalization of antibodies with transglutaminase |
| Prof. Roger Schibli, ETH Zurich | |
| 10:50 - 11:20 | PBD payloads for ADC - Current clinical status, technical challenges and opportunities |
| Dr. Francois D‘Hooge, Consultant | |
| 11:20 - 11:30 | Break |
| 11:30 - 12:00 | Chemo-enzymatic glycan conjugation of toxic payloads provides ADCs with superior therapeutic index |
| Dr. Marloes Wijdeven, Synaffix BV | |
| 12:00 - 12:30 | Amanitin-based ADCs as new therapeutic modalities for cancer therapy |
| Dr George Badescu, Heidelberg Pharma AG | |
| 12:30 - 13:00 | Modernizing ADC control strategies |
| Dr. Nathan Ihle, Immunomedics, Inc. | |
| 13:00 - 14:00 | Lunch |
| Technology insights, processing and services | |
| 14:00 - 14:30 | Accurate and robust methods for product characterization of unconjugated mAbs and conjugated ADCs |
| Dr. Daniel Galbraith, Merck, BioReliance | |
| 14:30 - 15:00 | Characterization of monodisperse oligo ethylene glycol ADC linkers |
| Dr. Tobias Haag, Merck | |
| 15:00 - 15:30 | ADC process development and case studies on the impact of small molecule impurities on the conjugation process and the clearance of organic solvent by TFF |
| Dr. Maxime Lampilas, Sanofi | |
| 15:30 - 16:00 | Process understanding and automated processing in development to ensure first pass manufacturing success of ADCs |
| Lisa McDermott, Merck | |
| 16:00 - 16:15 | Poster presentation and afternoon coffee: Demonstration of solvent compatibility and extractables profile for use of Mobius® assemblies in ADC processing |
| Merck | |
| 16:15 - 16:30 | Poster presentation and afternoon coffee: Mobius® mixing studies in ADC processing |
| Merck | |
| 16:30 - 17:00 | M Lab™ Collaboration Center tour |
| Merck | |
| 17:00 - 17:15 | Wrap-up and closing remarks |
| 18:00 - 21:00 | Post-event activity, reception and dinner in Strasbourg |
| 21:00 | End of the event |
* Agenda subject to change. Attendance to the ADC & Bioconjugation Symposium is limited and available to pharma/biopharma manufacturers only. The offer does not extend to any company that provides products or services to the pharma/biopharma industry. We reserve the right to revoke or refuse participation at any times. The event is free of charge, though registration is required. Refreshments, lunch and dinner are provided courtesy of Merck KGaA, Darmstadt, Germany. Travel costs, hotel accommodations and any other costs incurred are at the expense of the attendees.
Venue Information
M Lab™ Collaboration Center, Molsheim
The Symposium will take place at our M Lab™ Collaboration Center in Molsheim, France:
Millipore SAS
M Lab™ Collaboration Center
39 route industrielle de la Hardt
67120 Molsheim, France
(region of Strasbourg)