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505414 (±)-Epibatidine dihydrochloride - CAS 501684-93-1 - Calbiochem

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, Nicotinic Acetylcholine Receptors (nAChR) Agonist, Epibatidine

Primary Target: nAChR
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
501684-93-1C₁₁H₁₃ClN₂•2HCl•xH2O
Description
Overview

This product has been discontinued.



The most potent agonist known for nicotinic acetylcholine receptors (nAChR, Ki = 0.045 and 0.058 nM for natural (+) enantiomer and (-) enantiomer, respectively). Widely used for studying the functional roles of nAChRs in brain.
Catalogue Number505414
Brand Family Calbiochem®
Synonyms2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, Nicotinic Acetylcholine Receptors (nAChR) Agonist, Epibatidine
References
ReferencesDecker, W., et al., 1999. Biochem. Pharmacol. 58, 917.
Gerzanich, V., et al., 1995. Mol. Pharmacol. 48, 774.
Spande,X., et al., 1992. J. Am. Chem. Soc. 114, 3475.
Product Information
CAS number501684-93-1
FormWhite powder
Hill FormulaC₁₁H₁₃ClN₂•2HCl•xH2O
Chemical formulaC₁₁H₁₃ClN₂•2HCl•xH2O
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetnAChR
Primary Target K<sub>i</sub>0.045 nM
Purity≥99% by HPLC
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
505414 0

Documentation

References

Reference overview
Decker, W., et al., 1999. Biochem. Pharmacol. 58, 917.
Gerzanich, V., et al., 1995. Mol. Pharmacol. 48, 774.
Spande,X., et al., 1992. J. Am. Chem. Soc. 114, 3475.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-August-2013 JSW
Synonyms2-(6-chloropyridin-3-yl)-7-azabicyclo[2.2.1]heptane, Nicotinic Acetylcholine Receptors (nAChR) Agonist, Epibatidine
DescriptionThe most potent agonist known for nicotinic acetylcholine receptors (nAChR, Ki = 0.045 and 0.058 nM for natural (+) enantiomer and (-) enantiomer, respectively). Widely used for studying the functional roles of nAChRs in brain.
FormWhite powder
CAS number501684-93-1
Chemical formulaC₁₁H₁₃ClN₂•2HCl•xH2O
Structure formulaStructure formula
Purity≥99% by HPLC
SolubilityDMSO (4 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesDecker, W., et al., 1999. Biochem. Pharmacol. 58, 917.
Gerzanich, V., et al., 1995. Mol. Pharmacol. 48, 774.
Spande,X., et al., 1992. J. Am. Chem. Soc. 114, 3475.