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107478 1,2-Propanediol

EMPROVE® EXPERT Ph Eur,BP,ChP,USP

1,2-Propanediol MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 1,2-Propylene glycol

CAS #: 57-55-6 EC Number: 200-338-0 Molar Mass: 76.09 g/mol Chemical Formula: CH₃CH(OH)CH₂OH Hill Formula: C₃H₈O₂ Grade: Ph Eur,BP,ChP,USP
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Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaChemical FormulaMolar MassGrade Value
57-55-6200-338-0C₃H₈O₂CH₃CH(OH)CH₂OH76.09 g/molPh Eur,BP,ChP,USP
Description
Catalogue Number107478
Synonyms1,2-Propylene glycol
Description1,2-Propanediol
References
Product Information
CAS number57-55-6
EC number200-338-0
GradePh Eur,BP,ChP,USP
Hill FormulaC₃H₈O₂
Chemical formulaCH₃CH(OH)CH₂OH
Molar Mass76.09 g/mol
HS Code2905 32 00
Structure formula ImageStructure formula Image
Quality LevelMQ500
Applications
Biological Information
Physicochemical Information
Boiling point188 °C (1013 hPa)
Density1.036 g/cm3 (25 °C)
Explosion limit2.4 - 17.4 %(V)
Flash point99 °C
Ignition temperature371 °C
Melting Point-20 °C
pH value6 - 8 (100 g/l, H₂O, 20 °C)
Vapor pressure0.2 hPa (25 °C)
Refractive Index1.43 (20 °C)
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 19400 - 36000 mg/kg
LD 50 dermalLD50 Rabbit 20800 mg/kg
Safety Information according to GHS
RTECSTY2000000
Safety Information
Product Usage Statements
Storage and Shipping Information
Packaging Information
Transport Information
Supplemental Information
Specifications
Assay (GC)≥ 99.5 %
Identity (IR)conforms
Identity 1 (ChP) (GC)conforms
Identity C (USP) (GC)conforms
Appearance of the substanceconforms
Density (d 20 °C/20 °C)1.035 - 1.040
Density (d 25 °C/25 °C)1.035 - 1.037
Refractive index (n 20/D)1.431 - 1.433
Acidityconforms
Acidity (ChP)conforms
Chloride (Cl)≤ 70 ppm
Sulfate (SO₄)≤ 60 ppm
Diethylene glycol (GC)≤ 0.10 %
Ethylene glycol (GC)≤ 0.02 %
Related substances (GC) (Diethylene glycol)≤ 0.001 %
Related substances (GC) (Dipropylene glycol)≤ 0.1 %
Related substances (GC) (Tripropylene glycol)≤ 0.03 %
Related substances (GC) (1,2-Epoxypropane)≤ 0.001 %
Residual solvents (ICH Q3C)excluded by production process
Oxidizing substancesconforms
Reducing substancesconforms
Heavy metals≤ 0.0005 %
Arsenic≤ 0.0002 %
Sulfated ash≤ 0.005 %
Water≤ 0.2
Bacterial endotoxins≤ 2.5 I.U./ml
Total aerobic microbial count (TAMC)≤ 10²
Total combined yeasts/moulds count (TYMC)≤ 10¹
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities).
Class 1-3 elements are not likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Conforms to Ph Eur, BP, ChP, USP.

Documentation

Material Qualification Dossier

TitleVersion
10.1

Quality Management Dossier (Open Access)

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Operational Excellence Dossier

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1,2-Propanediol SDS

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Safety Data Sheet (SDS) 

1,2-Propanediol Certificates of Analysis

Product Number PackagingLot Number
107478

Certificates

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