Millipore Sigma Vibrant Logo

855017 2-Chlorotrityl chloride resin (100-200 mesh), 1% DVB

Novabiochem®

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
View Products on Sigmaaldrich.com
855017
View Pricing & Availability

Overview

Replacement Information
Description
Catalogue Number855017
Replaces01-64-0114
Brand Family Novabiochem®
Background InformationAn extremely versatile, acid-labile resin for the solid phase immobilization of carboxylic acids [1-6, 20], alcohols [7-9, 20], phenols [10-13, 20] and amines [14-20], imidazoles [20] and hydroxylamines [21, 22].

Release of these functionalities is generally achieved using 1-50% TFA in DCM containing 5% TIS, although carboxylic acids can also be cleaved from this support with AcOH/TFE/DCM [1-6], 0.5% TFA in DCM, or HFIP in DCM [23].

The product number for this product was previously 01-64-0114.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore below +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Colour (visual) white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Ala-Leu loaded resin)1.00 - 1.80 mmol/g
Swelling Volume (in CH₂Cl₂)2.0 - 5.0 ml/g
Total swelling volume acc. Houben Weyl (in CH2Cl2)≥ 4.2 ml/g
The polymer matrix is copoly (styrene-1 % DVB) 100 - 200 mesh.

Documentation

2-Chlorotrityl chloride resin (100-200 mesh), 1% DVB SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] K. Barlos, et al. (1989) Tetrahedron Lett., 30, 3947.
  • [2] K. Barlos, et al. (1989) Tetrahedron Lett., 30, 3943.
  • [3] K. Barlos, et al. (1991) Angew. Chem. Int. Ed. Engl., 30, 590.
  • [4] K. Barlos, et al. (1991) Int. J. Peptide Protein Res., 37, 513.
  • [5] K. Barlos, et al. (1991) Int. J. Peptide Protein Res., 38, 562.
  • [6] K. Barlos, et al. (1991) Int. J. Peptide Protein Res., 38, 555.
  • [7] H. Wenschuh, et al. in 'Peptides 1994, Proc. 23rd European Peptide Symposium', H. Maia (Eds), ESCOM, Leiden, 1995, pp. 287.
  • [8] H. Wenschuh, et al. (1995) J. Org. Chem., 60, 405.
  • [9] B. B. Shankar, et al. (1998) Tetrahedron Lett., 39, 2447.
  • [10] Z. Zhu & B. Mckittrick (1998) Tetrahedron Lett., 39, 7479.
  • [11] U. Heinelt, et al. (2001) Bioorg. Med. Chem. Lett., 11, 227.
  • [12] K. J. Elgie, et al. (2000) Tetrahedron Lett., 41, 2753.
  • [13] S. Batra, et al. (2000) Tetrahedron Lett., 41, 5971.
  • [14] M. Cardno, et al. (1995) J. Chem. Soc., Chem. Commun., 2163.
  • [15] I. A. Nash, et al. (1996) Tetrahedron Lett., 37, 2625.
  • [16] W. J. Hoekstra, et al. (1997) Tetrahedron Lett., 38, 2629.
  • [17] J. Perumattan, et al. (1998) Mol. Div., 3, 121.
  • [18] J. J. McNally, et al. (1998) Tetrahedron Lett., 39, 967.
  • [19] M. A. Youngman & S. L. Dax (1997) Tetrahedron Lett., 38, 6347.
  • [20] A. Bernhardt, et al. (1997) J. Peptide Res., 50, 143.
  • [21] S. L. Mellor, et al. (1997) Tetrahedron Lett., 38, 3311.
  • [22] M. M. Meloni & M. Taddei (2001) Org. Lett., 3, 337.
  • [23] R. Bollhagen, et al. (1994) J. Chem. Soc., Chem. Commun., 2559.