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MABS817 Anti-AGT, clone 1B1 Antibody

Detect AGT using this Anti-AGT, clone 1B1 Antibody validated for use in Western Blotting.

Anti-AGT, clone 1B1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Developmental Signaling Gene Symbol: AGT, SERPINA8 UniProt Number: P01019
MABS817
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWBMAscitesMonoclonal Antibody
      Description
      Catalogue NumberMABS817
      ReplacesMABC123
      DescriptionAnti-AGT, clone 1B1 Antibody
      Alternate Names
      • Angiotensinogen
      • Serpin A8 -angiotensin II
      • Angiotensin-4
      • Angiotensin 3-8
      • Angiotensin IV
      • Ang IV
      • Angiotensin 1-9
      • Angiotensin 1-7
      • Angiotensin 1-5
      • Angiotensin 1-4
      • AGT
      Background InformationAngiotensinogen (AGT) is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
      References
      Product Information
      FormatAscites
      PresentationMouse monoclonal IgG2bascitic fluid containing 0.03% sodium azide.
      Quality LevelMQ300
      Applications
      ApplicationDetect AGT using this Anti-AGT, clone 1B1 Antibody validated for use in Western Blotting.
      Key Applications
      • Western Blotting
      Biological Information
      ImmunogenPurified recombinant fragment of human AGT expressed in E. Coli.
      Clone1B1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • AGT
      • SERPINA8
      Purification MethodUnpurified
      UniProt Number
      Molecular Weight~53 kDa observed. Uncharacterized bands may be observed in some lysate(s).
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in human plasma.

      Western Blotting Analysis (WB): A 1:500-2,000 dilution of this antibody detected AGT in human plasma.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at -20°C from date of receipt.
      Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS817 04055977172355