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PC713 Anti-Aldehyde Dehydrogenase 1 (488-501) Goat pAb

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-ALDH1, Anti-RALDH1, Anti-Retinaldehyde Dehydrogenase 2

PC713
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Gt
      Description
      Overview

      This product has been discontinued.





      Recognizes the ~37 kDa and 50 kDa ALDH1 protein in 293 cells and mouse spleen tissue. May also recognize ALDH1A2 that is alternatively spliced under certain conditions.
    • Antibody Target Gene Symbol: ADH1A
    • Target Synonym: ADH1, ADH1 ALPHA, ADH1A1
    • Entrez Gene Name: alcohol dehydrogenase 1A (class I), alpha polypeptide
    • Hu Entrez ID: 124
      		•
      Catalogue NumberPC713
      Brand Family Calbiochem®
      SynonymsAnti-ALDH1, Anti-RALDH1, Anti-Retinaldehyde Dehydrogenase 2
      Application Data
      Detection of human Aldehyde Dehydrogenase 1 by immunoblotting. Samples: Mock transfection of HEK293 cells (lane 1) and HEK293 cells overexpressing ALDH1A1 (lane 2). Primary antibody: Anti-Aldehyde Dehydrogenase 1 (488-501) Goat pAb (Cat. No. PC713) (0.1 µg/ml). Detection: chemiluminescence.
      References
      ReferencesVermot, J., et al. 2000. Endocrinology 141, 3638.
      Ren, S., et al. 1999. Drug Metab. Dispos. 27, 133.
      Product Information
      FormLiquid
      FormulationIn Tris saline, 0.5% BSA, pH 7.3.
      Positive controlHEK293 cells or mouse spleen
      Preservative≤0.1% sodium azide
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1-3 µg/ml, chemiluminescence)
      Application CommentsMay also recognize ALDH1A2, which is an alternatively spliced variant that occurs under certain conditions. Antibody should be titrated for optimal results in individual systems.
      Biological Information
      Immunogena synthetic peptide (EVKTVTVKISQKNS) corresponding to amino acids 488-501 of ALDH1A1
      ImmunogenHuman
      HostGoat
      IsotypeIgG
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      PC713 0

      Documentation

      References

      Reference overview
      Vermot, J., et al. 2000. Endocrinology 141, 3638.
      Ren, S., et al. 1999. Drug Metab. Dispos. 27, 133.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision16-October-2007 RFH
      SynonymsAnti-ALDH1, Anti-RALDH1, Anti-Retinaldehyde Dehydrogenase 2
      ApplicationImmunoblotting (1-3 µg/ml, chemiluminescence)
      Application Data
      Detection of human Aldehyde Dehydrogenase 1 by immunoblotting. Samples: Mock transfection of HEK293 cells (lane 1) and HEK293 cells overexpressing ALDH1A1 (lane 2). Primary antibody: Anti-Aldehyde Dehydrogenase 1 (488-501) Goat pAb (Cat. No. PC713) (0.1 µg/ml). Detection: chemiluminescence.
      DescriptionPurified goat polyclonal antibody. Recognizes the ~37 kDa and the ~50 kDa forms of aldehyde dehydrogenase.
      BackgroundAldehyde dehydrogenase 1 (ALDH1) is involved in the production of retinoic acid from its precursor retinaldehyde, and in drug metabolism.
      HostGoat
      Immunogen speciesHuman
      Immunogena synthetic peptide (EVKTVTVKISQKNS) corresponding to amino acids 488-501 of ALDH1A1
      IsotypeIgG
      Specieshuman, mouse
      Positive controlHEK293 cells or mouse spleen
      FormLiquid
      FormulationIn Tris saline, 0.5% BSA, pH 7.3.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsMay also recognize ALDH1A2, which is an alternatively spliced variant that occurs under certain conditions. Antibody should be titrated for optimal results in individual systems.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesVermot, J., et al. 2000. Endocrinology 141, 3638.
      Ren, S., et al. 1999. Drug Metab. Dispos. 27, 133.