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195111 Anti-BACE1, C-Terminal (485-501) Rabbit pAb

Anti-BACE1, C-Terminal (485-501), rabbit polyclonal, recognizes both the immature and mature forms of the BACE1. It is validated for WB, IF, IHC, IP, and RIA.

Anti-BACE1, C-Terminal (485-501) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-B690

195111
  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, M, RRbPolyclonal Antibody
      Description
      Overview

      This product has been discontinued.



      Recognizes both the immature and mature forms of the BACE1 protein.
      Catalogue Number195111
      Brand Family Calbiochem®
      SynonymsAnti-B690
      References
      ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunofluorescence
      Immunohistochemistry
      Immunoprecipitation
      Radioimmunoassay
      Application NotesImmunoblotting (1:500-1:1000)
      Immunofluorescence (1:200)
      Immunohistochemistry (see comments)
      Immunoprecipitation (3 µl/reaction)
      Radioimmunoassay (3-5 µl/reaction)
      Application CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      195111 0

      Documentation

      Anti-BACE1, C-Terminal (485-501) Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-BACE1, C-Terminal (485-501) Rabbit pAb Certificates of Analysis

      TitleLot Number
      195111

      References

      Reference overview
      Yan, R., et al. 2001. J. Biol. Chem. 276, 36788.

      Brochure

      Title
      Alzheimer's Disease Brochure & Technical Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision27-June-2007 RFH
      SynonymsAnti-B690
      ApplicationImmunoblotting (1:500-1:1000)
      Immunofluorescence (1:200)
      Immunohistochemistry (see comments)
      Immunoprecipitation (3 µl/reaction)
      Radioimmunoassay (3-5 µl/reaction)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes both the immature and mature forms of BACE1.
      Backgroundβ-secretase has been identified as a novel membrane-bound aspartyl protease named BACE1 (β-site amyloid precursor protein cleaving enzyme 1). It is one of two endopeptidases that cleave the β-amyloid precursor protein (APP) resulting in the accumulation of the β-amyloid deposits involved in the development of Alzheimer's disease.
      HostRabbit
      Immunogen speciesHuman
      Immunogena synthetic peptide (CLRQQHDDFADDISLLK) corresponding to amino acids 485-501 of human BACE1, conjugated to KLH
      IsotypeIgG
      Specieshuman, mouse, rat
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsThis antibody is also reported to work for immunohistochemistry. Variables associated with assay conditions will dictate the optimal working dilution.
      Storage Avoid freeze/thaw
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesYan, R., et al. 2001. J. Biol. Chem. 276, 36788.