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AB5314 Anti-Carboxypeptidase H Antibody, CT

Anti-Carboxypeptidase H Antibody, C-terminus is an antibody against Carboxypeptidase H for use in IP, WB & IC.

Anti-Carboxypeptidase H Antibody, CT MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Metabolism Research Sub-Category: Enzymes & Biochemistry Gene Symbol: CPE, CPH, EC 3.4.17.10 UniProt Number: P16870
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AB5314
100 µL  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      H, M, RIP, WB, ICCRbSerumPolyclonal Antibody
      Description
      Catalogue NumberAB5314
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Carboxypeptidase H Antibody, CT
      Alternate Names
      • CPH
      • Carboxypeptidase E
      References
      Product Information
      FormatSerum
      PresentationSerum with 0.02% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Carboxypeptidase H Antibody, C-terminus is an antibody against Carboxypeptidase H for use in IP, WB & IC.
      Key Applications
      • Immunoprecipitation
      • Western Blotting
      • Immunocytochemistry
      Application NotesImmunocytochemistry on AtT-20 cell line: 1:100-1:500.

      Western blot: 1:500-1:2,000. Carboxypeptidase H precursor migrates at 53 kDa while active enzyme migrates at about 48 kDa.

      Immunoprecipitation: 1:250-1:1,000

      Optimal working dilutions must be determined by end user.
      Biological Information
      ImmunogenSynthetic peptide corresponding to the C-terminus of Carboxypepdidase H conjugated to KLH.
      EpitopeC-terminus
      HostRabbit
      SpecificityC-terminus of Carboxypepdidase H.
      Species Reactivity
      • Human
      • Mouse
      • Rat
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThis gene encodes a carboxypeptidase that cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. It is a peripheral membrane protein. The protein specifically binds regulated secretory pathway proteins, including prohormones, but not constitutively secreted proteins. Mutations in this gene are implicated in type II diabetes.
      Gene Symbol
      • CPE
      • CPH
      • EC 3.4.17.10
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P16870 # Removes residual C-terminal Arg or Lys remaining after initial endoprotease cleavage during prohormone processing. Processes proinsulin.
      COFACTOR: Binds 1 zinc ion per subunit (By similarity).
      SIZE: 476 amino acids; 53151 Da
      SUBCELLULAR LOCATION: Secreted. Note=Secretory granules of pancreatic islets, adrenal gland, pituitary and brain.
      SIMILARITY: SwissProt: P16870 ## Belongs to the peptidase M14 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain frozen at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB5314 04053252624407

      Documentation

      Anti-Carboxypeptidase H Antibody, CT SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Carboxypeptidase H Antibody, CT Certificates of Analysis

      TitleLot Number
      RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY - 2161093 2161093
      RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY - 2396298 2396298
      RABBIT ANTI-CARBOXYPEPTIDASE H - 3239839 3239839
      RABBIT ANTI-CARBOXYPEPTIDASE H - 3998959 3998959
      RABBIT ANTI-CARBOXYPEPTIDASE H POLYCLONAL ANTIBODY -2506275 2506275

      Data Sheet

      Title
      RABBIT ANTI-CARBOXYPEPTIDASE H