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ABC100 Anti-Hyaluronan synthase 3 Antibody

Detect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.

Anti-Hyaluronan synthase 3 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: HAS3 UniProt Number: O00219
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ABC100
100 µg  
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      Overview

      Replacement Information

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HWB, IHCRbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberABC100
      DescriptionAnti-Hyaluronan synthase 3 Antibody
      Alternate Names
      • Hyaluronan synthase 3
      • Hyaluronate synthase 3
      • Hyaluronic acid synthase 3
      • HA synthase 3
      Background InformationHyaluronan synthase 3 (HAS3) is one of three enzymes, located at the plasma membrane, that synthesizes the glycosaminoglycan hyaluronan. Hyaluronan is involved in cell proliferation, differentiation, angiogenesis, and tumor development, among other cellular processes. Hyaluronan synthase 3 creates the low—molecular-weight hyaluronan, whereas hyaluronan synthase 1 and 2 create high molecular weight isoforms.
      References
      Product Information
      FormatAffinity Purified
      Control
      • SW620 cell lysate
      PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationDetect Hyaluronan synthase 3 using this Anti-Hyaluronan synthase 3 Antibody validated for use in Western Blotting & IHC.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:500-1,000 dilution from a representative lot detected Hyaluronan synthase 3 in human liver and human kidney tissues.
      Biological Information
      ImmunogenKLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Hyaluronan synthase 3.
      EpitopeCytoplasmic domain
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityThis antibody recognizes both isoforms at the cytoplasmic domain of Hyaluronan synthase 3.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • HAS3
      Purification MethodAffinity Purfied
      UniProt Number
      Molecular Weight~28/60 kDa observed. An uncharacterized band appears at ~70 kDa in some lysates. The calculated molecular weight of this protein is 63 kDa for isoform 1 and 31 kDa for isoform 2, but can be observed at ~60 and ~28 kDa.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blot in SW620 cell lysate.

      Western Blot Analysis: 2 µg/mL of this antibody detected Hyaluronan synthase 3 on 10 µg of SW620 cell lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      ABC100 04053252441455

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Anti-Hyaluronan synthase 3 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Hyaluronan synthase 3 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Hyaluronan synthase 3 - 2495487 2495487
      Anti-Hyaluronan synthase 3 - 2564038 2564038
      Anti-Hyaluronan synthase 3 - Q2030495 Q2030495
      Anti-Hyaluronan synthase 3 -2618512 2618512
      Anti-Hyaluronan synthase 3 Polyclonal Antibody 2949137

      References

      Reference overviewPub Med ID
      Cytotoxic diterpenoids from Isodon enanderianus.
      Xiang, Wei, et al.
      Planta Med., 69: 1031-5 (2003)  2003

      Show Abstract       		14735442 14735442

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies