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MABC713 Anti-KEAP1, clone 7G4B10 Antibody

Anti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.

Anti-KEAP1, clone 7G4B10 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Apoptosis & Cancer Research Sub-Category: Apoptosis - Additional Gene Symbol: KEAP1, INRF2, KLHL19 UniProt Number: Q14145
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MABC713
100 µg  
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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIHC, FC, ELISAMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABC713
      DescriptionAnti-KEAP1, clone 7G4B10 Antibody
      Alternate Names
      • Kelch-like ECH-associated protein 1
      • Cytosolic inhibitor of Nrf2
      • INrf2
      • Kelch-like protein 19
      • KEAP1
      Background InformationKelch-like ECH-associated protein 1, also known as Cytosolic inhibitor of Nrf2 or INrf2 or Kelch-like protein 19, and encoded by the gene name KEAP1 or INRF2 or KLHL19, acts as a substrate adapter protein for the E3 ubiquitin ligase complex and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome. KEAP1 shuttles between the cytoplasm and the nucleus and is widely expressed with high levels found in skeletal muscle.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal in PBS containing up to 0.1% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-KEAP1, clone 7G4B10 Antibody is an antibody against KEAP1 for use in IHC, flow cytometry & ELISA.
      Key Applications
      • Immunohistochemistry
      • Flow Cytometry
      • ELISA
      Application NotesFlow Cytometry Analysis: A 1:200-400 dilution from a representative lot detected KEAP1 in HeLa cells.

      ELISA: A representative lot detected control Antigen (100 ng) and Antigen (10 ng, 50 ng, 100 ng) in ELISA (Direct).
      Biological Information
      ImmunogenPurified recombinant fragment of human KEAP1 expressed in E. Coli
      Clone7G4B10
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostMouse
      Species Reactivity
      • Human
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • KEAP1
      • INRF2
      • KLHL19
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight70 kDa calculated
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceImmunohistochemistry Analysis: A 1:200-1,000 dilution from a representative lot detected KEAP1 in bladder cancer and cerebellum tissues.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABC713 04053252957277

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      Categories

      Life Science Research > Antibodies and Assays > Primary Antibodies