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489475 Anti-LRP-5/6 Mouse mAb (1A12)

This Anti-LRP-5/6 Mouse mAb (1A12) is validated for use in Immunoblotting for the detection of LRP-5/6.

Anti-LRP-5/6 Mouse mAb (1A12) MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Low Density Lipoprotein Receptor-Related Protein-5/6

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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, MMMonoclonal Antibody
      Description
      Overview

      This product has been discontinued.



      Recognizes the ~175 kDa full-length LRP-6 protein and a ~145 kDa proteolytic fragment.
      Catalogue Number489475
      Brand Family Calbiochem®
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein-5/6
      References
      ReferencesLi, L., et al. 2001. J. Biol. Chem. 277, 5977.
      Product Information
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-glycine, 25% glycerol, 0.5% BSA, pH 7.0.
      Preservative≤0.1% sodium azide
      Quality LevelMQ100
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Application NotesImmunoblotting (1-2 µg/ml)
      Application CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Biological Information
      Immunogena synthetic peptide (DTGTDRIEVTR) corresponding to amino acids 421-431 of the human low density lipoprotein receptor-related protein 6 (LRP-6)
      ImmunogenHuman
      Clone1A12
      HostMouse
      IsotypeIgG2b
      Species Reactivity
      • Human
      • Mouse
      Antibody TypeMonoclonal Antibody
      Concentration Label Please refer to vial label for lot-specific concentration
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      489475 0

      Documentation

      Anti-LRP-5/6 Mouse mAb (1A12) SDS

      Title

      Safety Data Sheet (SDS) 

      References

      Reference overview
      Li, L., et al. 2001. J. Biol. Chem. 277, 5977.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-August-2007 RFH
      SynonymsAnti-Low Density Lipoprotein Receptor-Related Protein-5/6
      ApplicationImmunoblotting (1-2 µg/ml)
      DescriptionPurified mouse monoclonal antibody. Recognizes the ~175 kDa full length LRP-5/6 and the ~145 kDa proteolytic fragment.
      BackgroundLRP-5 and LRP-6 are members of the LDL receptor family involved in the Wnt signaling pathway. The peptide sequence corresponding to amino acid residues 421-431 of the human low density lipoprotein receptor-related protein (LRP) is completely conserved between LRP-5 and LRP-6, as well as between human and mouse.
      HostMouse
      Immunogen speciesHuman
      Immunogena synthetic peptide (DTGTDRIEVTR) corresponding to amino acids 421-431 of the human low density lipoprotein receptor-related protein 6 (LRP-6)
      Clone1A12
      IsotypeIgG2b
      Specieshuman, mouse
      FormLiquid
      FormulationIn 150 mM NaCl, 10 mM Tris-glycine, 25% glycerol, 0.5% BSA, pH 7.0.
      Concentration Label Please refer to vial label for lot-specific concentration
      Preservative≤0.1% sodium azide
      CommentsVariables associated with assay conditions will dictate the proper working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesLi, L., et al. 2001. J. Biol. Chem. 277, 5977.