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MABN742 Anti-Neuroligin-1, clone 1C9.1 Antibody

This Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.

Anti-Neuroligin-1, clone 1C9.1 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Neuroscience, Neuroscience Research Sub-Category: Synapse & Synaptic Biology, Growth Cones & Axon Guidance Gene Symbol: NLGN1, KIAA1070, NL1 UniProt Number: Q8N2Q7
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MABN742
100 µg  
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      Overview

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      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      R, HWB, IHCMPurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABN742
      DescriptionAnti-Neuroligin-1, clone 1C9.1 Antibody
      Alternate Names
      • neuroligin 1
      • NLGN1
      • neuroligin-1
      Background InformationNeuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of excitatory synapses for their normal, functional development, and is necessary to the regulation of synaptic plasticity and the development of long-term memory within the adult amygdala in mammals. It is believed to participate in cell-cell-interaction through the assembly of intracellular junction by the binding of beta-neurexins, and may also be a factor in the maintenance and assembly of synaptic junctions. It is also thought to have involvement in excitatory synaptic specification. Within brain tissue, Neuroligin-1 is primarily observed in neurons and spinal cord.
      References
      Product Information
      FormatPurified
      PresentationPurified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationThis Anti-Neuroligin-1, clone 1C9.1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of Neuroligin-1.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      Application NotesImmunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Neuroligin-1 in human cerebral cortex, rat cerebellum and rat cerebral cortex tissue.
      Biological Information
      ImmunogenGST-tagged recombinant protein corresponding to the extracellular domain of Human Neuroligin-1.
      EpitopeExtracellular domain
      Clone1C9.1
      ConcentrationPlease refer to lot specific datasheet.
      HostMouse
      IsotypeIgG2aκ
      Species Reactivity
      • Rat
      • Human
      Antibody TypeMonoclonal Antibody
      Entrez Gene Number
      Gene Symbol
      • NLGN1
      • KIAA1070
      • NL1
      Purification MethodProtein G Purified
      UniProt Number
      Molecular Weight~94 kDa observed
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting in rat brain tissue lysate.

      Western Blotting Analysis: 1.0 µg/mL of this antibody detected Neuroligin-1 in 10 µg of rat brain tissue lysate.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABN742 04053252996214

      Documentation

      Anti-Neuroligin-1, clone 1C9.1 Antibody SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-Neuroligin-1, clone 1C9.1 Antibody Certificates of Analysis

      TitleLot Number
      Anti-Neuroligin-1, clone 1C9.1 - Q2454910 Q2454910
      Anti-Neuroligin-1, clone 1C9.1 - 3476006 3476006
      Anti-Neuroligin-1, clone 1C9.1 - 3887811 3887811
      Anti-Neuroligin-1, clone 1C9.1 Monoclonal Antibody 3079182
      Anti-Neuroligin-1, clone 1C9.1 Monoclonal Antibody 2929159

      Brochure

      Title
      Pathways and Biomarkers of Glutamatergic Synapse Flyer