Millipore Sigma Vibrant Logo

MABS1214 Anti-PEG (methoxy group) Antibody, clone RM105

Anti-PEG (methoxy group), clone RM105 is an antibody against PEG (methoxy group) for use in WB, IH, ELISA.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Signaling Research Sub-Category: Epitope Tags Gene Symbol: N/A
View Products on Sigmaaldrich.com
MABS1214
100 µL  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

      Special Offers

       

      Contact Customer Service

      Overview

      Replacement Information

      Special Offers

      100% Performance Guaranteed

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      AWB, IHC, ELISARbAffinity PurifiedMonoclonal Antibody
      Description
      Catalogue NumberMABS1214
      DescriptionAnti-PEG (methoxy group) Antibody, clone RM105
      Alternate Names
      • PEG
      • pegylation
      • methoxy group
      • Polyethylene glycol
      • polyethylene oxide
      • PEO
      • polyoxyethylene
      • POE
      Background InformationPolyethylene glycol (PEG) is a polyether compound with many applications from industrial manufacturing to medicine. PEG is also known as polyethylene oxide (PEO) or polyoxyethylene (POE), depending on its molecular weight. PEG is a family of long chain polymers attached to a glycerine backbone. Some of the properties of PEG are nonionic, nontoxic, biocompatible, strongly hydrophilic polymer, which has a large exclusion volume in aqueous solution. PEGylation is the act of covalently coupling a PEG structure to another larger molecule, for example, a therapeutic protein, which is then referred to as a PEGylated protein. The covalent attachment of PEG (PEGylation) is commonly used to modify a variety of proteins and drugs. Some of the therapeutical benefits of PEGylated molecules include increased bioavailability, increased blood circulation of the drug, optimized pharmacokinetics, decreased immunogenicity, and decreased frequency of administration. Additional benefits of PEGylated molecules include decelerated renal excretion, improved stability towards proteolysis, increased solubility of the biopharmaceutical in aqueous solutions, increased hydrodynamic radius, reduced immunogenicity and proteolytic cleavage. This antibody reacts to the terminal methoxy group of Polyethylene glycol.
      References
      Product Information
      FormatAffinity Purified
      PresentationPurified rabbit monoclonal IgG in PBS buffer containing 1% BSA and 0.09% sodium azide
      Quality LevelMQ100
      Applications
      ApplicationAnti-PEG (methoxy group), clone RM105 is an antibody against PEG (methoxy group) for use in WB, IH, ELISA.
      Key Applications
      • Western Blotting
      • Immunohistochemistry
      • ELISA
      Application NotesImmunohistochemistry Analysis: 0.5 μg/mL of this antibody detected PEG (methoxy)-BSA in injected mouse liver and kidney
      ELISA Analysis: Multiple concentrations of this antibody was used to detect three different BSA-PEG conjugates (5K, 40K and 40K branched)
      Biological Information
      Immunogenrecombinant protein corresponding to All PEG (methoxy group).
      CloneRM105
      ConcentrationPlease refer to lot specific datasheet.
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • All
      Antibody TypeMonoclonal Antibody
      Gene Symbol
      • N/A
      Purification MethodProtein A Purfied
      Molecular WeightBSA is 66 kD, methoxyPEG is 5 kD. Additional bands above 66 kD is due to different levels of conjugation and dimerization.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssuranceEvaluated by Western Blotting on recombinant methoxyPEG conjugated BSA

      Western Blotting Analysis: A 1:1;000 dilution of this antibody detected PEG (methoxy group) on conjugated recombinant BSA
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
      Packaging Information
      Material Size100 µL
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      MABS1214 04055977115857

      Documentation

      Anti-PEG (methoxy group) Antibody, clone RM105 SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-PEG (methoxy group) Antibody, clone RM105 Certificates of Analysis

      TitleLot Number
      Anti-PEG (methoxy group), clone RM105 QVP1406132
      Anti-PEG (methoxy group), clone RM105 - VP1903220 VP1903220
      Anti-PEG (methoxy group), clone RM105 - VP1908300 VP1908300
      Anti-PEG (methoxy group), clone RM105 - VP2207134 VP2207134
      Anti-PEG (methoxy group), clone RM105 - VP2307210 VP2307210
      Anti-PEG (methoxy group), clone RM105 - VP2309280 VP2309280
      Anti-PEG (methoxy group), clone RM105 - VP2311291 VP2311291
      Anti-PEG (methoxy group), clone RM105 - VP2403071 VP2403071
      Anti-PEG (methoxy group), clone RM105 - VP2405021 VP2405021
      Anti-PEG (methoxy group), clone RM105 - VP2407245 VP2407245
      Show more