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516557 Anti-PGC-1, C-Terminal (777-797) Rabbit pAb

This Anti-PGC-1, C-Terminal (777-797) Rabbit pAb is validated for use in ELISA, Immunoblotting, Immunohistochemistry for the detection of PGC-1, C-Terminal (777-797).

Anti-PGC-1, C-Terminal (777-797) Rabbit pAb MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: Anti-Ligand Effect Modulator 6, Anti-PPARγ Coactivator 1

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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityHostAntibody Type
      H, MRbPolyclonal Antibody
      Description
      OverviewRecognize the ~92-105 kDa (apparent MW) PGC-1 protein.
      Catalogue Number516557
      Brand Family Calbiochem®
      SynonymsAnti-Ligand Effect Modulator 6, Anti-PPARγ Coactivator 1
      References
      ReferencesPuigserver, P., et al. 1998. Cell 92, 829.
      Product Information
      FormLiquid
      FormulationIn PBS.
      Quality LevelMQ100
      Applications
      Key Applications Enzyme-Linked Immunosorbent Assay
      Immunoblotting (Western Blotting)
      Immunohistochemistry
      Application NotesELISA (1:50,000)
      Immunoblotting (1:1000)
      Immunohistochemistry (1:300)
      Application CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Biological Information
      Immunogena synthetic peptide [(C)SKYDSLDFDSLLKEAQRSLRR] corresponding to amino acids 777-797 of the human PPARγ Coactivator 1 protein
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Species Reactivity
      • Human
      • Mouse
      Antibody TypePolyclonal Antibody
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage ≤ -70°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      516557 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Anti-PGC-1, C-Terminal (777-797) Rabbit pAb SDS

      Title

      Safety Data Sheet (SDS) 

      Anti-PGC-1, C-Terminal (777-797) Rabbit pAb Certificates of Analysis

      TitleLot Number
      516557

      References

      Reference overview
      Puigserver, P., et al. 1998. Cell 92, 829.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-February-2015 JSW
      SynonymsAnti-Ligand Effect Modulator 6, Anti-PPARγ Coactivator 1
      ApplicationELISA (1:50,000)
      Immunoblotting (1:1000)
      Immunohistochemistry (1:300)
      DescriptionImmunoaffinity purified rabbit polyclonal antibody. Recognize the ~92-105 kDa (apparent MW) PGC-1 protein.
      BackgroundPGC-1 (PPARγ-coactivator-1) is a coactivator that promotes transcription through the formation of a complex that includes steroid receptor coactivator-1 (SRC-1) and CREB binding protein (CBP)/p300. The binding of PGC-1 to the hinge domain of PPAR (peroxisome proliferator activated receptor) stimulates a conformational change in PGC-1 that permits binding of SRC-1 and CBP/p300, resulting in a large increase in transcriptional activity. Murine PGC-1 has been also reported to enhance the expression of uncoupling protein-1.
      HostRabbit
      Immunogen speciesHuman
      Immunogena synthetic peptide [(C)SKYDSLDFDSLLKEAQRSLRR] corresponding to amino acids 777-797 of the human PPARγ Coactivator 1 protein
      IsotypeIgG
      Specieshuman, mouse
      FormLiquid
      FormulationIn PBS.
      CommentsVariables associated with assay conditions will dictate the optimal working dilution.
      Storage Avoid freeze/thaw
      ≤ -70°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
      Toxicity Standard Handling
      ReferencesPuigserver, P., et al. 1998. Cell 92, 829.