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CA1010 Anti-Pax3 Rabbit pAb

CA1010
  
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      Overview

      Replacement Information

      Key Spec Table

      Host
      Rb
      Description
      Overview

      This product has been discontinued.





      Recognizes the ~56 kDa Pax3 protein, the ~97 kDa Pax3-FHKR fusion protein, and possibly other Pax3 splice variants.
      Catalogue NumberCA1010
      Brand Family Calbiochem®
      References
      ReferencesHollenbach, A.D., et al. 2002. Biochim. Biophys. Acta 1574, 321.
      Lagutina, I., et al. 2002. Mol. Cell. Biol. 22, 7204.
      Lam, P.Y., et al. 1999. Mol. Cell. Biol. 19, 594.
      Product Information
      FormLiquid
      FormulationUndiluted serum.
      Negative controlNormal rabbit IgG (Cat. No. NI01)
      Positive controlMyoblasts from p1-5 mouse pups
      PreservativeNone
      Applications
      Key Applications Immunoblotting (Western Blotting)
      Immunocytochemistry
      Application NotesImmunoblotting (1:1000)
      Immunocytochemistry (1:500)
      Application CommentsMay also detect other Pax3 splice variants. Antibody should be titrated for optimal results in an individual systems.
      Biological Information
      Immunogena recombinant protein consisting of amino acids 1-347 of human Pax3 fused to GST
      ImmunogenHuman
      HostRabbit
      IsotypeIgG
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Dry Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Avoid freeze/thaw Avoid freeze/thaw
      Do not freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Anti-Pax3 Rabbit pAb Certificates of Analysis

      TitleLot Number
      CA1010

      References

      Reference overview
      Hollenbach, A.D., et al. 2002. Biochim. Biophys. Acta 1574, 321.
      Lagutina, I., et al. 2002. Mol. Cell. Biol. 22, 7204.
      Lam, P.Y., et al. 1999. Mol. Cell. Biol. 19, 594.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-August-2007 RFH
      ApplicationImmunoblotting (1:1000)
      Immunocytochemistry (1:500)
      DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the ~56 kDa Pax3 protein and the ~97 kDa Pax3-FHKR fusion protein.
      BackgroundPax3 is a transcription factor involved in myogenesis. It has been shown to bind calmyrin, the EF-hand calcium binding protein, and Daxx, a transcriptional co-repressor. Chromosomal translocation resulting in the Pax3-FKHR fusion protein may play a role in alveolar rhabdomyo-sarcoma development.
      HostRabbit
      Immunogen speciesHuman
      Immunogena recombinant protein consisting of amino acids 1-347 of human Pax3 fused to GST
      IsotypeIgG
      Specieshuman, mouse
      Positive controlMyoblasts from p1-5 mouse pups
      Negative controlNormal rabbit IgG (Cat. No. NI01)
      FormLiquid
      FormulationUndiluted serum.
      PreservativeNone
      CommentsMay also detect other Pax3 splice variants. Antibody should be titrated for optimal results in an individual systems.
      Storage -20°C
      Avoid freeze/thaw
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
      Toxicity Standard Handling
      ReferencesHollenbach, A.D., et al. 2002. Biochim. Biophys. Acta 1574, 321.
      Lagutina, I., et al. 2002. Mol. Cell. Biol. 22, 7204.
      Lam, P.Y., et al. 1999. Mol. Cell. Biol. 19, 594.