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AB9471 Anti-Prostacyclin Receptor Antibody

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AB9471
50 µg  
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      Overview

      Replacement Information

      Key Spec Table

      Species ReactivityKey ApplicationsHostFormatAntibody Type
      HIH(P)RbAffinity PurifiedPolyclonal Antibody
      Description
      Catalogue NumberAB9471
      Brand Family Chemicon®
      Trade Name
      • Chemicon
      DescriptionAnti-Prostacyclin Receptor Antibody
      References
      Product Information
      FormatAffinity Purified
      PresentationAffinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide.
      Quality LevelMQ100
      Applications
      ApplicationAnti-Prostacyclin Receptor Antibody is an antibody against Prostacyclin Receptor for use in IH(P).
      Key Applications
      • Immunohistochemistry (Paraffin)
      Application NotesImmunohistochemistry on paraffin embedded tissue sections.

      Optimal working dilutions must be determined by the end user.
      Biological Information
      ImmunogenSynthetic peptide from the N-terminal extracellular domain of human Prostacyclin Receptor.
      ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
      HostRabbit
      SpecificityRecognizes Prostacyclin Receptor.
      Species Reactivity
      • Human
      Antibody TypePolyclonal Antibody
      Entrez Gene Number
      Entrez Gene SummaryThe protein encoded by this gene is a member of the G-protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.
      Gene Symbol
      • PTGIR
      • PRIPR
      • MGC102830
      • IP
      UniProt Number
      UniProt SummaryFUNCTION: SwissProt: P43119 # Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.
      SIZE: 386 amino acids; 40956 Da
      SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
      PTM: Palmitoylation of either Cys-308 or Cys-311 is sufficient to maintain functional coupling to G(s) and signaling. & Isoprenylation does not influence ligand binding but is required for efficient coupling to the effectors adenylyl cyclase and phospholipase C.
      SIMILARITY: SwissProt: P43119 ## Belongs to the G-protein coupled receptor 1 family.
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Availability by Geography
      • This product is not available for sale in Japan.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsMaintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
      Packaging Information
      Material Size50 µg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      AB9471 04053252320279