Millipore Sigma Vibrant Logo

SCT046 BioTracker CyP AP Live Cell Dye

Live cell imaging dye for alkaline phosphatase (AP) for cancer and stem cell applications.

BioTracker CyP AP Live Cell Dye MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Cell Based Assays
View Products on Sigmaaldrich.com
SCT046
1 mg  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information

      Key Spec Table

      Key Applications
      Cell Based Assays
      Description
      Catalogue NumberSCT046
      DescriptionBioTracker CyP AP Live Cell Dye
      OverviewAlkaline Phosphatase (AP) catalyzes the hydrolysis of the phosphate group in alkaline media. AP is an essential enzyme and widely distributes in a variety of tissues such as liver, intestine, kidney, bone, and placenta. Abnormal AP levels have been shown in numerous cancers, bone disease and liver dysfunction. AP is also expressed by pluripotent stem cells such as ES and IPS cells.

      The BioTracker CyP AP dye is a live cell near-infrared (NIR) fluorescent imaging probe for alkaline phosphatase. With its long emission wavelength, the probe is suitable for monitoring AP levels in both in vivo and in vitro tissues and cells. The probe possesses deep tissue penetration, less damage to the biological samples, and lower interference from the background fluorescence compared to other AP probes.

      Spectral Properties
      Absorbance: 690nm
      Emission: 738nm

      References
      Nie SX et al. Facile and Sensitive Near-Infrared Fluorescence Probe for the Detection of Endogenous Alkaline Phosphatase Activity In Vivo. Anal Chem. 2017 Jun 20;89(12):6854-6860.
      Alternate Names
      • Live cell imaging probe
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized
      Applications
      ApplicationLive cell imaging dye for alkaline phosphatase (AP) for cancer and stem cell applications.
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity: ≥ 98% confirmed by HNMR, LC-MS and HPLC and elemental analysis
      Molar Mass: 528.55 g/mol
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker CyP AP Live Cell Dye at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size1 mg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT046 04054839532405