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SCT260 BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator

This perylene derivative probe containing oligooxyethylene is designed for the detection of lipid peroxides in live cells.

SCT260
250 μg  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT260
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      DescriptionBioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator
      OverviewThis perylene derivative probe containing oligooxyethylene is designed for detection of lipid peroxides. BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator emits intense fluorescence by lipid peroxide specific oxidation in organic solvents such as ethanol. This is the only RUO probe that can specifically detect lipid peroxides.
      SCT260's oxidized form is nearly nonfluorescent in an aqueous media, but produces a bright fluorescence in lipophilic sites such as in cell membranes.

      This probe is light-sensitive, and should be pipetted as quickly as possible, preferably within one minute. Protect working solutions and samples from light, and use within one day of preparing working solution.
      Alternate Names
      • lipid peroxide probe
      • lipid peroxide live cell dye
      • live cell ferroptosis indicator
      Background InformationThis perylene derivative containing oligooxyethylene is designed for the detection of lipid peroxides. SCT260 emits intense fluorescence by lipid peroxide-specific oxidation in organic solvents such as ethanol. Among fluorescent probes that detect Reactive Oxygen Species(ROS), SCT260 is the only compound that can specifically detect lipid peroxides. Because the excitation and emission wavelengths of the oxidized probe are 524 nm and 535 nm, respectively, phototoxicity to and autofluorescence from the sample can be minimized. The tetraethyleneglycol group linked to one end of diisoquinoline ring enhances solubility and dispersibility in aqueous buffer.
      References
      Product Information
      Detection methodFluorescence
      FormatLyophilized solid
      PresentationLyophilized. Dark red solid.
      Quality LevelMQ100
      Applications
      ApplicationThis perylene derivative probe containing oligooxyethylene is designed for the detection of lipid peroxides in live cells.
      Key Applications
      • Cell Based Assays
      • Fluorescence
      • Flow Cytometry
      • Fluorescence Activated Cell Sorting (FACS)
      Application NotesLive cell probe for fluorescent detection of lipid peroxidation by fluorescence microscopy or flow cytometry. SCT260 is a valuable reagent for ferroptosis research.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality Assurance
      Purity: ≥ 90% confirmed by HPLC. Authenticated by NMR.
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker™ Green Lipid Peroxide Live Cell Ferroptosis Indicator at 2 - 8 °C, protected from light.
      Packaging Information
      Material Size250 μg
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT260 04065269218135

      Documentation