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SCT211 BioTracker Green Sulfane Sulfur live cell dye

Live Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and ploysulfide (H2Sn).

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SCT211
3 x 60 nmol  
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      Overview

      Replacement Information
      Description
      Catalogue NumberSCT211
      DescriptionBioTracker Green Sulfane Sulfur live cell dye
      OverviewIntracellularly abundant sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and polysulfide (H2Sn) play important roles to maintain intracellular reducing environments.

      BioTracker Green Sulfane Sulfur Live Cell Dye is a FRET-based fluorescence probe to specifically detect the intracellular sulfane sulfur species. It shows only weak fluorescence without sulfane sulfur, and reversibly fluoresces in response to micromolar concentrations of sulfane sulfur. Its reaction is highly specific and has minimal to no reactivity with H2S, cysteine residues, and sulfur oxides. The dye is a cell permeable diacetylated form which is hydrolyzed by intracellular esterases to generate a metabolite which is retained within the cells. Thus it is suitable to monitor intracellular concentration of sulfane sulfur via live-cell imaging.

      Spectral Properties
      Absorbance (max): 495nm
      Emission (max): 525nm

      References
      Takano Y et al. Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application. Chem Commun. 2017. Jan 17; 53(6):1064-1067.
      Alternate Names
      • SSip-1 DA, 60 nmol x 3
      References
      Product Information
      Detection methodFluorescence
      PresentationLyophilized
      Applications
      ApplicationLive Cell imaging probe for sulfane sulfur species including persulfide (R-S-SH), polysulfide (R-S-Sn-S-R) and ploysulfide (H2Sn).
      Key Applications
      • Cell Based Assays
      Application NotesLive cell fluorescent imaging. Green fluorescence.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Quality AssurancePurity: ≥ 65% (LC)
      Usage Statement
      • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
      Storage and Shipping Information
      Storage ConditionsStore BioTracker Green Sulfane Sulfur Live Cell Dye at -20°C, desiccate and protect from light
      Note: Centrifuge vial briefly to collect contents at bottom of vial before opening.
      Packaging Information
      Material Size3 x 60 nmol
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      SCT211 04061841697633