203294 Sigma-AldrichBisindolylmaleimide III, Hydrochloride
A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC₅₀ = 26 nM).
More>> A potent, cell-permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC₅₀ = 26 nM). Less<<Bisindolylmaleimide III, Hydrochloride MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Synonyms: 2-[1-(3-Aminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, HCl
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Overview
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Key Spec Table
CAS # | Empirical Formula |
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683775-59-9 | C₂₃H₂₀N₄O₂ · HCl |
Description | |
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Overview | This product has been discontinued. Please refer to our complete listing of bisindolylmaleimide compounds and other protein kinase C inhibitors for possible alternatives. |
Catalogue Number | 203294 |
Brand Family | Calbiochem® |
Synonyms | 2-[1-(3-Aminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide, HCl |
References | |
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References | Fabre, S., and Prudhomme, M. 1993. Bioorg. Med. Chem. 1, 193. Davis, P.D., et al. 1992. J. Med. Chem. 35, 177. Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771. |
Product Information | |
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CAS number | 683775-59-9 |
Form | Red solid |
Hill Formula | C₂₃H₂₀N₄O₂ · HCl |
Chemical formula | C₂₃H₂₀N₄O₂ · HCl |
Structure formula Image |
Applications |
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Biological Information | |
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Primary Target | PKC |
Primary Target IC<sub>50</sub> | 26 nM |
Secondary target | PKA (IC₅₀ = 500 nM) |
Purity | ≥95% by HPLC |
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Cell permeable | Y |
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Documentation
Bisindolylmaleimide III, Hydrochloride SDS
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Bisindolylmaleimide III, Hydrochloride Certificates of Analysis
Title | Lot Number |
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203294 |
References
Reference overview |
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Fabre, S., and Prudhomme, M. 1993. Bioorg. Med. Chem. 1, 193. Davis, P.D., et al. 1992. J. Med. Chem. 35, 177. Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771. |