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407135 Caged Ins(1,4,5)P₃, Trisodium Salt - Calbiochem

Photolabile derivative of Ins(1,4,5)P₃ that is not biologically active and is not metabolized by endogenous phosphatase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: D-myo-Inositol 1,4,5-Trisphosphate, P4(5)-1-(2-Nitrophenyl)ethyl Ester, 3Na

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407135
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₄H₁₉NO₁₇P₃ · 3Na

Pricing & Availability

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407135-10UG
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      		 Plastic ampoule 10 μg
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      407135-1SET
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          		 Glass bottle 1 set
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          Description
          OverviewPhotolabile derivative of Ins(1,4,5)P3 that is not biologically active and is not metabolized by endogenous phosphatase. A mixture of two isomers with a cage present on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P3.
          Extinction coefficient (265 nm, H2O): 4240 M-1cm-1.
          Note: 1 set = 10 x 10 µg.
          Catalogue Number407135
          Brand Family Calbiochem®
          SynonymsD-myo-Inositol 1,4,5-Trisphosphate, P4(5)-1-(2-Nitrophenyl)ethyl Ester, 3Na
          References
          ReferencesWalker, J.W., et al. 1987. Nature 327, 249.
          Product Information
          ATP CompetitiveN
          FormWhite to off-white solid or powder
          Hill FormulaC₁₄H₁₉NO₁₇P₃ · 3Na
          Chemical formulaC₁₄H₁₉NO₁₇P₃ · 3Na
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetPhotolabile derivative of Ins(1,4,5)P3 that is not biologically active
          Purity≥90% by 31P-NMR
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Protect from Moisture Protect from moisture
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications
          Global Trade Item Number
          Catalogue Number GTIN
          407135-10UG 04055977188585
          407135-1SET 04055977188578

          Documentation

          Caged Ins(1,4,5)P₃, Trisodium Salt - Calbiochem SDS

          Title

          Safety Data Sheet (SDS) 

          Caged Ins(1,4,5)P₃, Trisodium Salt - Calbiochem Certificates of Analysis

          TitleLot Number
          407135

          References

          Reference overview
          Walker, J.W., et al. 1987. Nature 327, 249.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision22-July-2020 JSW
          SynonymsD-myo-Inositol 1,4,5-Trisphosphate, P4(5)-1-(2-Nitrophenyl)ethyl Ester, 3Na
          DescriptionPhotolabile derivative of Ins(1,4,5)P3 that is not biologically active and is not metabolized by endogenous phosphatase (extinction coefficient: 4240 M-1cm-1; 265 nm, H2O). A mixture of two isomers with a cage on either the 4 or 5 position. Can be selectively released by irradiation with a short pulse of light of about 360 nm to produce a concentration jump of Ins(1,4,5)P3.
          FormWhite to off-white solid or powder
          Chemical formulaC₁₄H₁₉NO₁₇P₃ · 3Na
          Structure formulaStructure formula
          Purity≥90% by 31P-NMR
          SolubilityH₂O (1 mg/ml)
          Storage Protect from moisture
          Protect from light
          -20°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesWalker, J.W., et al. 1987. Nature 327, 249.