218746 Sigma-AldrichCaspase-1 Inhibitor VI - Calbiochem
Caspase-1 Inhibitor VI, Z-YVAD-FMK, is a potent, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5.
More>> Caspase-1 Inhibitor VI, Z-YVAD-FMK, is a potent, cell-permeable, and irreversible inhibitor of caspase-1, caspase-4, and caspase-5. Less<<Synonyms: Z-YVAD-FMK
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Overview
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Key Spec Table
| Empirical Formula |
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| C₃₁H₃₉FN₄O₉ |
| Description | |
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| Overview | A potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5. |
| Catalogue Number | 218746 |
| Brand Family | Calbiochem® |
| Synonyms | Z-YVAD-FMK |
| References | |
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| References | Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105. |
| Product Information | |
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| ATP Competitive | N |
| Form | White powder |
| Hill Formula | C₃₁H₃₉FN₄O₉ |
| Chemical formula | C₃₁H₃₉FN₄O₉ |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | caspase-1 |
| Purity | ≥95% by HPLC or TLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Z-Tyr-Val-Ala-Asp(OMe)-CH₂F* |
| Dimensions |
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| Materials Information |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information |
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| Transport Information |
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| Supplemental Information |
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| Specifications |
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| Global Trade Item Number | |
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| Catalogue Number | GTIN |
| 218746 | 0 |
Documentation
Caspase-1 Inhibitor VI - Calbiochem SDS
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Caspase-1 Inhibitor VI - Calbiochem Certificates of Analysis
| Title | Lot Number |
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| 218746 |
References
| Reference overview |
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| Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105. |
Brochure
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| Caspases and other Apoptosis Related Tools Brochure |



