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218776 Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem

The Caspase-9 Inhibitor II, Cell-Permeable controls the biological activity of Caspase-9. This small molecule/inhibitor is primarily used for Cancer applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: LEHD-CHO, Cell-permeable

Primary Target: caspase-4, caspase-5, caspase-9
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218776
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₉₇H₁₆₂N₂₂O₂₅

Pricing & Availability

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218776-1MG
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      		 Glass bottle 1 mg
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      Description
      OverviewA potent, cell-permeable, and reversible inhibitor of caspase-9. May also inhibit caspase-4 and caspase-5. The N-terminal sequence (amino acids 1-16) corresponds to the hydrophobic region of the signal peptide of Kaposi fibroblast growth factor and confers cell permeability to the peptide.
      Catalogue Number218776
      Brand Family Calbiochem®
      SynonymsLEHD-CHO, Cell-permeable
      References
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Product Information
      ATP CompetitiveN
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₉₇H₁₆₂N₂₂O₂₅
      Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
      Hygroscopic Hygroscopic
      ReversibleY
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcaspase-4, caspase-5, caspase-9
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      218776-1MG 07790788048617

      Documentation

      Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Caspase-9 Inhibitor II, Cell-Permeable - Calbiochem Certificates of Analysis

      TitleLot Number
      218776

      References

      Reference overview
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision04-June-2008 RFH
      SynonymsLEHD-CHO, Cell-permeable
      DescriptionA potent, cell-permeable and reversible inhibitor or caspase-9.
      FormWhite lyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₉₇H₁₆₂N₂₂O₂₅
      Peptide SequenceAc-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Leu-Glu-His-Asp-CHO
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.