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219380 Cefotaxime, Sodium Salt - CAS 64485-93-4 - Calbiochem

Potent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7²-(Z)-(O-methyloxime) Acetate, Na

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      64485-93-4C₁₆H₁₆N₅O₇S₂ · Na
      Description
      OverviewPotent β-lactamase-resistant antibiotic of cephalosporin class. Active against Gram-positive and Gram-negative organisms, including Gram-negative anaerobes. Inhibits cell wall synthesis.
      Catalogue Number219380
      Brand Family Calbiochem®
      Synonyms7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7²-(Z)-(O-methyloxime) Acetate, Na
      References
      ReferencesMolinari, G., et al. 1991. J. Chemotherap. 3, 6.
      Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother. 35, 2057.
      Product Information
      CAS number64485-93-4
      FormWhite crystalline solid
      Hill FormulaC₁₆H₁₆N₅O₇S₂ · Na
      Chemical formulaC₁₆H₁₆N₅O₇S₂ · Na
      Hygroscopic Hygroscopic
      Optical rotationOptical rotation: +58° to +64° (c = 1, H₂O).
      Quality LevelMQ100
      Applications
      Biological Information
      Purity≥91% by HPLC (dry basis)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      RTECSXI0250000
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +15°C to +30°C
      Protect from Light Protect from light
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 10 days at 4°C or for up to 13 weeks at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      219380 0

      Documentation

      Required Licenses

      Title
      PRODUCTO REGULADO POR LA SECRETARÍA DE SALUD

      Cefotaxime, Sodium Salt - CAS 64485-93-4 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Cefotaxime, Sodium Salt - CAS 64485-93-4 - Calbiochem Certificates of Analysis

      TitleLot Number
      219380

      References

      Reference overview
      Molinari, G., et al. 1991. J. Chemotherap. 3, 6.
      Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother. 35, 2057.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2008 RFH
      Synonyms7-[2-(2-Amino-4-thiazolyl)glyoxylamido]-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate 7²-(Z)-(O-methyloxime) Acetate, Na
      DescriptionPotent β-lactamase-resistant antibiotic of cephalosporin class. Active against gram-positive and gram-negative organisms, including gram-negative anaerobes. Inhibits cell wall synthesis. Has an optimal pH of 4.5-6.5.
      FormWhite crystalline solid
      CAS number64485-93-4
      RTECSXI0250000
      Chemical formulaC₁₆H₁₆N₅O₇S₂ · Na
      Purity≥91% by HPLC (dry basis)
      SolubilityH₂O (250 mg/ml)
      Storage Protect from light
      +15°C to +30°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C) for long term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 10 days at 4°C or for up to 13 weeks at -20°C.
      Toxicity Standard Handling
      Merck USA index14, 1933
      ReferencesMolinari, G., et al. 1991. J. Chemotherap. 3, 6.
      Vallee, F., and LeBel, M. 1991. Antimicrob. Agents Chemother. 35, 2057.