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856000 Cysteamine 2-chlorotrityl resin

Novabiochem®

Cysteamine 2-chlorotrityl resin MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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856000
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Overview

Replacement Information
Description
Catalogue Number856000
Replaces01-64-0107
Brand Family Novabiochem®
Background InformationAn acid-labile resin for the preparation of N-acyl or N-alkyl cysteamines. The free amino functionality of the resin-bound cysteamine can be readily acylated or reductively alkylated using standard procedures. Cleavage can be effected with electrophilic oxidants such as I2 or Tl3 to produce a dimeric disulfide bridged product, or with 50-100% TFA to give the monomeric sulfhydryl product. Peptidylaminoethylthiols produced in this manner have been used to prepare PEG-conjugates by chemoselective ligation to pegylated maleimide [1]. This method is particularly useful for forming intramolecular disulfide bridges in molecules containing two thiol groups where one is protected with Acm.

For a similar application, see [2, 3, 4].

The product number for this product was previously 01-64-0107.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
HS Code3903 90 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)1.00 - 2.00 mmol/g
Swelling Volume (in DMF)lot specific result
The polymer matrix is copoly (styrene-1% DVB), 200 - 400 mesh.

Documentation

Cysteamine 2-chlorotrityl resin SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] J. Zhang, et al. Poster 162 presented at the 16 American Peptide Symposium, Minneapolis, 1999.
  • [2] A. v. Vliet, et al. in 'Innovation & Perspectives in Solid Phase Synthesis, 2nd International Symposium', R. Epton (Eds), Intercept UK Ltd., Andover, 1992, pp. 475.
  • [3] A. v. Vliet, et al. in 'Peptides 1992, Proc. 22nd European Peptide Symposium', C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 279.
  • [4] A. v. Vliet, et al. in 'Peptides, Chemistry, Structure, & Biology, Proc. 13th American Peptide Symposium', R. S. Hodges & J. A. Smith (Eds), ESCOM, Leiden, 1994, pp. 151.