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851055 DMAP

Overview

Replacement Information

Key Spec Table

CAS #EC NumberHill FormulaMolar Mass
1122-58-3214-353-5C₇H₁₀N₂122.17 g/mol
Description
Catalogue Number851055
Replaces01-62-0004
Brand Family Novabiochem®
Alternate Names
  • 4-Dimethylaminopyridine
Background InformationCatalyst for esterification and amidation reagents [1-3].

The product number for this product was previously 01-62-0004.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number1122-58-3
EC number214-353-5
Hill FormulaC₇H₁₀N₂
Molar Mass122.17 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationDMAP 4-(Dimethylamino)pyridine Novabiochem®. CAS 1122-58-3, pH 11 (60 g/l, H₂O, 20 °C).
Biological Information
Physicochemical Information
Boiling point138 - 140 °C (24 hPa)
Flash point124 °C
Ignition temperature420 °C
Melting Point112 °C
pH value10.23 (0.1 g/l, H₂O, 22 °C)
Bulk density520 kg/m3
Solubility60 g/l
Dimensions
Materials Information
Toxicological Information
LD 50 oralLD50 Rat 140 mg/kg
LD 50 dermalLD50 Rabbit 90 mg/kg
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Pictogram(s)
Hazard Statement(s)H301 + H331: Toxic if swallowed or if inhaled.
H310: Fatal in contact with skin.
H315: Causes skin irritation.
H318: Causes serious eye damage.
H370: Causes damage to organs.
H411: Toxic to aquatic life with long lasting effects.
Precautionary Statement(s)P262: Do not get in eyes, on skin, or on clothing.
P273: Avoid release to the environment.
P280: Wear protective gloves/ protective clothing/ eye protection/ face protection/ hearing protection.
P301 + P310: IF SWALLOWED: Immediately call a POISON CENTER/doctor.
P302 + P352 + P310: IF ON SKIN: Wash with plenty of water. Immediately call a POISON CENTER/doctor.
P305 + P351 + P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Signal WordDanger
RTECSUS9230000
Storage class6.1A Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
WGKWGK 3 highly hazardous to water
Safety Information
Categories of dangertoxic, irritant
Product Usage Statements
Storage and Shipping Information
StorageStore below +30°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 2811 , 6.1, II
Declaration (transport by air) IATA-DGRUN 2811 , 6.1, II
Declaration (transport by sea) IMDG-CodeUN 2811 , 6.1, II
Supplemental Information
Specifications
Colour (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (GC, area%)≥ 99.0 % (a/a)
Melting range (lower value)≥ 110 °C
Melting range (upper value)≤ 113 °C

Documentation

DMAP SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] S. S. Wang, et al. (1981) Int. J. Peptide Protein Res., 18, 459.
  • [2] J.-P. Gamet, et al. (1984) Tetrahedron, 40, 1995.
  • [3] K. Takeda, et al. (1991) Synthesis, 1991, 689.