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854000 Dde-Lys(Fmoc)-OH

Dde-Lys(Fmoc)-OH Novabiochem®. CAS 156648-40-7, molar mass 532.63 g/mol.

Dde-Lys(Fmoc)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 156648-40-7 Molar Mass: 532.63 g/mol Hill Formula: C₃₁H₃₆N₂O₆
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854000
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
156648-40-7C₃₁H₃₆N₂O₆532.63 g/mol
Description
Catalogue Number854000
Replaces04-12-5201
Brand Family Novabiochem®
Alternate Names
  • N-α-1-(4,4-Dimethyl-2,6-dioxocyclohex-1-ylidene)ethyl-N-ε-Fmoc-L-lysine
Background InformationQuasi-orthogonally-protected Lys derivative. The Fmoc group can be removed selectively by treatment with piperidine; the Dde group is cleaved with 2% hydrazine in DMF [1]. When removing Dde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [2].

Also available Fmoc-Lys(Dde)-OH 852057.

This derivative has been employed in Fmoc SPPS to facilitate the introduction of biotin to the side-chain of lysine [3].

The product number for this product was previously 04-12-5201.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number156648-40-7
Hill FormulaC₃₁H₃₆N₂O₆
Molar Mass532.63 g/mol
HS Code2924 29 70
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationDde-Lys(Fmoc)-OH Novabiochem®. CAS 156648-40-7, molar mass 532.63 g/mol.
Biological Information
Physicochemical Information
Melting Point>70 °C (decomposition)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Colour (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.5 % (a/a)
Purity (TLC(157B))≥ 97 %
Purity (TLC(CMA2))≥ 97 %
Assay (HPLC, area%)≥ 96.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 90.0 %
Water (K. F.)≤ 1.00 %
For TLC-Systems see our General Catalog

Documentation

Dde-Lys(Fmoc)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] B. W. Bycroft, et al. (1993) J. Chem. Soc., Chem. Commun., 778.
  • [2] B. Rohwedder, et al. (1998) Tetrahedron Lett., 39, 1175.
  • [3] J. Mack, et al. (1999) Lett. Pept. Sci., 6, 135.