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324696 Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem

A specific chromogenic substrate for human neutrophil elastase.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
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324696
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Overview

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324696-10MG
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      		 Glass bottle 10 mg
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      Description
      OverviewA specific chromogenic substrate for human neutrophil elastase (Kcat/Km = 120,000 vs. 2700 for pancreatic elastase). Cleavage can be monitored at ~410 nm. Sold on the basis of substrate content.
      Catalogue Number324696
      Brand Family Calbiochem®
      References
      ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
      Product Information
      CAS number70967-90-7
      ATP CompetitiveN
      FormLyophilized
      FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
      Hill FormulaC₂₇H₃₈N₆O₉
      Chemical formulaC₂₇H₃₈N₆O₉
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetChromogenic substrate for human neutrophil elastase
      Primary Target IC<sub>50</sub>Kcat/Km = 120,000 vs. 2700 for pancreatic elastase
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      324696-10MG 07790788059323

      Documentation

      Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Elastase Substrate I, Colorimetric - CAS 70967-90-7 - Calbiochem Certificates of Analysis

      TitleLot Number
      324696

      References

      Reference overview
      Barrett, A.J., et al. 1989. Biochim. J. 260, 259.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision12-May-2008 JSW
      DescriptionSpecific chromogenic substrate for human neutrophil elastase (kcat/Km = 120,000 versus pancreatic elastase: kcat/Km = 2,700). Cleavage can be monitored at 410 nm using ε = 8,800.
      FormLyophilized
      FormulationLyophilized from a solution containing 90 mg D-mannitol and 10 mg substrate.
      CAS number70967-90-7
      Chemical formulaC₂₇H₃₈N₆O₉
      Peptide SequenceMeOSuc-Ala-Ala-Pro-Val-pNA
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage Protect from moisture
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesBarrett, A.J., et al. 1989. Biochim. J. 260, 259.
      Nakajima, K., et al. 1979. J. Biol. Chem. 254, 4027.