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341326 Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem

The Fatty Acid Synthase Inhibitor, Cpd 10v, also referenced under CAS 1027354-00-2, controls the biological activity of Fatty. This small molecule/inhibitor is primarily used for Cancer applications.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor

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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      1027354-00-2C₂₃H₁₅ClN₂O₃
      Description
      Overview

      This product has been discontinued.



      A hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
      Catalogue Number341326
      Brand Family Calbiochem®
      Synonyms7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
      References
      ReferencesRivkin, A., et al. 2006. J. med. Chem. 16, 4620.
      Product Information
      CAS number1027354-00-2
      FormWhite solid
      Hill FormulaC₂₃H₁₅ClN₂O₃
      Chemical formulaC₂₃H₁₅ClN₂O₃
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥98% by HPLC
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Regulatory Review
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      341326 0

      Documentation

      Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Fatty Acid Synthase Inhibitor, Cpd 10v - CAS 1027354-00-2 - Calbiochem Certificates of Analysis

      TitleLot Number
      341326

      References

      Reference overview
      Rivkin, A., et al. 2006. J. med. Chem. 16, 4620.

      Brochure

      Title
      New Products: Volume 3, 2012
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision20-April-2012 JSW
      Synonyms7-chloro-4-hydroxy-3-(2ʹ-methoxybiphenyl-3-yl)-2-oxo-1,2-dihydroquinoline-6-carbonitrile, FAS inhibitor
      DescriptionA hydroxyquinolinone derivative that acts as a potent reversible inhibitor of type 1 fatty acid synthase (FAS) (IC50 = 19 nM) when enzyme activity is monitored by following the synthesis of free coenzyme A (CoA-SH).
      FormWhite solid
      Intert gas (Yes/No) Packaged under inert gas
      CAS number1027354-00-2
      Chemical formulaC₂₃H₁₅ClN₂O₃
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityDMSO (50 mg/ml; clear, colorless solution)
      Storage Protect from light
      -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Regulatory Review
      ReferencesRivkin, A., et al. 2006. J. med. Chem. 16, 4620.