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852067 Fmoc-Arg(Pbf)-OH

Fmoc-Arg(Pbf)-OH Novabiochem®. CAS 154445-77-9, molar mass 648.78 g/mol.

Fmoc-Arg(Pbf)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 154445-77-9 Molar Mass: 648.77 g/mol Hill Formula: C₃₄H₄₀N₄O₇S
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
154445-77-9C₃₄H₄₀N₄O₇S648.77 g/mol
Description
Catalogue Number852067
Replaces04-12-1145
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-NG-(2,2,4,6,7-pentamethyldihydrobenzofuran-5-sulfonyl)-L-arginine
Background InformationThe standard derivative for the introduction of Arg in Fmoc SPPS [1, 2]. The Pbf side-chain protecting group is removed with TFA approximately 1-2 times faster than Pmc.

In the preparation of peptides containing both Arg and Trp, it is recommended that this derivative is used in conjunction with Fmoc-Trp(Boc)-OH (852050).

The product number for this product was previously 04-12-1145.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number154445-77-9
Hill FormulaC₃₄H₄₀N₄O₇S
Molar Mass648.77 g/mol
HS Code2935 90 29
Structure formula ImageStructure formula Image
Quality LevelMQ400
Applications
ApplicationFmoc-Arg(Pbf)-OH Novabiochem®. CAS 154445-77-9, molar mass 648.78 g/mol.
Biological Information
Physicochemical Information
Melting Point>65 °C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -10°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to off white
Appearance of substance (visual)powder
Color index (0,5 M in DMF)≤ 150 Hazen
Identity (IR)passes test
Enantiomeric purity≥ 99.8 % (a/a)
Purity (HPLC)≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-ß-Ala-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Arg(Pbf)-Arg(Pbf)-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Arg-OH (HPLC)≤ 0.1 % (a/a)
Assay free amino acid (HPLC)≤ 0.2 %
Purity (TLC(011C))≥ 98 %
Purity (TLC(157B))≥ 98 %
Solubility (12,5 mmol in 25 ml DMF)clearly soluble
Assay (acidimetric)≥ 90.0 %
Water (K. F.)≤ 2.0 %
Ethyl acetate (HS-GC)≤ 1.0 %
Acetate (IC)≤ 0.02 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Arg(Pbf)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] L. A. Carpino, et al. (1993) Tetrahedron Lett., 34, 7829.
  • [2] C. G. Fields, et al. (1993) Tetrahedron Lett., 34, 6661.