Millipore Sigma Vibrant Logo

852119 Fmoc-Asn(Dmcp)-OH

Fmoc-Asn(Dmcp)-OH Novabiochem®. CAS 172947-19-2, molar mass 436.5 g/mol.

Fmoc-Asn(Dmcp)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 172947-19-2 Molar Mass: 436.5 g/mol Hill Formula: C₂₅H₂₈N₂O₅
View Products on Sigmaaldrich.com
852119
View Pricing & Availability

Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
172947-19-2C₂₅H₂₈N₂O₅436.5 g/mol
Description
Catalogue Number852119
Replaces04-12-1291
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-β-(1-cyclopropyl-1-methylethyl)-L-asparagine
Background InformationA superior derivative to Fmoc-Asn(Trt)-OH for the synthesis of Asn-containing peptides by Fmoc SPPS. Fmoc-Asn(Dmcp)-OH is more soluble in DMF than Fmoc-Asn(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility.

The product number for this product was previously 04-12-1291.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number172947-19-2
Hill FormulaC₂₅H₂₈N₂O₅
Molar Mass436.5 g/mol
HS Code2924 29 70
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Asn(Dmcp)-OH Novabiochem®. CAS 172947-19-2, molar mass 436.5 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Purity (TLC(CMA2))≥ 98.0 %
Assay (HPLC, area%)≥ 97.8 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 95.0 %
Water (K. F.)≤ 2.00 %
Enantiomeric purity≥ 99.5 % (a/a)
For TLC-Systems see our General Catalog

Documentation

Fmoc-Asn(Dmcp)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] L. A. Carpino, et al. (1995) J. Org. Chem., 60, 7718.