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852072 Fmoc-Asp-OAll

Fmoc-Asp-OAll Novabiochem®. CAS 144120-53-6, molar mass 395.41 g/mol.

Fmoc-Asp-OAll MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 144120-53-6 Molar Mass: 395.4 g/mol Hill Formula: C₂₂H₂₁NO₆
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
144120-53-6C₂₂H₂₁NO₆395.4 g/mol
Description
Catalogue Number852072
Replaces04-12-1157
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-L-aspartic acid α-allyl ester
Background InformationOrthogonally-protected building block for the synthesis of head-to-tail cyclic peptides [1-5].

The α-allyl ester can be selectively removed in the presence of Fmoc- and tBu-based protecting groups by treatment with Pd(Ph3P)4/ CHCl3/AcOH/NMM [6], thereby facilitating the synthesis of branched esters, amides, lactones and lactams incorporating an aspartyl unit.

The product number for this product was previously 04-12-1157.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number144120-53-6
Hill FormulaC₂₂H₂₁NO₆
Molar Mass395.4 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Asp-OAll Novabiochem®. CAS 144120-53-6, molar mass 395.41 g/mol.
Biological Information
Physicochemical Information
Melting Point95 °C decomposes
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore below +30°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)conforms
Enantiomeric purity≥ 99.0 % (a/a)
Purity (TLC(CMA2))≥ 98 %
Purity (TLC(157A))≥ 98 %
Assay (HPLC, area%)≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 97.0 %
Water (K. F.)≤ 1.5 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Asp-OAll SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] W. Bannwarth, et al. (1992) Tetrahedron Lett., 33, 4557.
  • [2] F. Albericio, et al. (1993) Tetrahedron Lett., 34, 1549.
  • [3] J. Eichler, et al. (1994) Pept. Res., 7, 300.
  • [4] J. Eichler, et al. in 'Peptides 1994, Proc. 23rd European Peptide Symposium', H. Maia (Eds), ESCOM, Leiden, 1994, pp. 461.
  • [5] J. Eichler, et al. in 'Solid Phase Synthesis & Combinatorial Libraries, 4th International Symposium', R. Epton (Eds), Mayflower Scientific Ltd., Birmingham, 1996, pp. 201.
  • [6] S. A. Kates, et al. in 'Peptides, Chemistry, Structure & Biology, Proc. 13th American Peptide Symposium', ESCOM, Leiden, 1994, pp. 113.