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852084 Fmoc-Dab(ivDde)-OH

Fmoc-Dab(ivDde)-OH Novabiochem®. CAS 607366-21-2, molar mass 546.65 g/mol.

Fmoc-Dab(ivDde)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 607366-21-2 Molar Mass: 546.65 g/mol Hill Formula: C₃₂H₃₈N₂O₆
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
607366-21-2C₃₂H₃₈N₂O₆546.65 g/mol
Description
Catalogue Number852084
Replaces04-12-1196
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-γ-1-(4,4-dimethyl-2,6-dioxocyclohex-1-ylidene)-3-methylbutyl-L-diaminobutanoic acid
Background InformationThis orthogonally-protected diaminobutyric acid derivative is based on the hindered Dde variant ivDde. The side-chain ivDde group is considerably more stable to piperidine than Dde and is less prone to migrate from protected to unprotected side-chains [1] and from side-chain to α-amino group [2].

When removing ivDde in the presence of allyl-based protecting groups, allyl alcohol should be included in the deprotection solution to prevent reduction of the allyl group [3].

The product number for this product was previously 04-12-1196.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number607366-21-2
Hill FormulaC₃₂H₃₈N₂O₆
Molar Mass546.65 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Dab(ivDde)-OH Novabiochem®. CAS 607366-21-2, molar mass 546.65 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Colour (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.5 % (a/a)
Purity (TLC(157A))≥ 98 %
Purity (TLC(157B))≥ 98 %
Assay (HPLC, area%)≥ 95.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Water (K. F.)≤ 1.00 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Dab(ivDde)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] S. R. Chhabra, et al. (1998) Tetrahedron Lett., 39, 1603.
  • [2] R. Wilhelm, personal communication.
  • [3] B. Rohwedder, et al. (1998) Tetrahedron Lett., 39, 1175.
  • [4] S. K. Sharma, et al. (1999) J. Peptide Res., 53, 501.