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852120 Fmoc-Gln(Dmcp)-OH

Fmoc-Gln(Dmcp)-OH Novabiochem®. CAS 172947-20-5, molar mass 450.53 g/mol.

Fmoc-Gln(Dmcp)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 172947-20-5 Molar Mass: 450.53 g/mol Hill Formula: C₂₆H₃₀N₂O
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852120
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
172947-20-5C₂₆H₃₀N₂O450.53 g/mol
Description
Catalogue Number852120
Replaces04-12-1292
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-γ-(1-cyclopropyl-1-methylethyl)-L-glutamine
Background InformationA superior derivative to Fmoc-Gln(Trt)-OH for the synthesis of Gln-containing peptides by Fmoc SPPS. Fmoc-Gln(Dmcp)-OH is more soluble in DMF than Fmoc-Gln(Trt)-OH, thereby facilitating coupling reactions at higher concentration. Cleavage of the Dmcp group is rapid, even when the residue is located at the N-terminus of a peptide. Coupling of Dmcp-protected derivatives is faster than that of the corresponding hindered Trt derivatives. Dmcp-protected peptides have enhanced solubility.

The product number for this product was previously 04-12-1292.

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References
Product Information
CAS number172947-20-5
Hill FormulaC₂₆H₃₀N₂O
Molar Mass450.53 g/mol
HS Code2924 29 70
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Gln(Dmcp)-OH Novabiochem®. CAS 172947-20-5, molar mass 450.53 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
For TLC-Systems see our General Catalog
Assay (acidimetric)≥ 90.0 %
Assay (HPLC, area%)≥ 98.0 % (a/a)
Water (K. F.)≤ 1.00 %
Identity (IR)passes test
Solubility (1 mmole in 2 ml DMF)passes test
Color (visual)passes test
Appearance of substance (visual)passes test
Purity (TLC(CMA2))≥ 98 %
Enantiomeric purity≥ 99.5 % (a/a)

Documentation

Fmoc-Gln(Dmcp)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] L. A. Carpino, et al. (1995) J. Org. Chem., 60, 7718.