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852045 Fmoc-Gln(Trt)-OH

Fmoc-Gln(Trt)-OH Novabiochem®. CAS 132327-80-1, molar mass 610.72 g/mol.

Fmoc-Gln(Trt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 132327-80-1 Molar Mass: 610.72 g/mol Hill Formula: C₃₉H₃₄N₂O₅
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
132327-80-1C₃₉H₃₄N₂O₅610.72 g/mol
Description
Catalogue Number852045
Replaces04-12-1090
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-γ-trityl-L-glutamine
Background InformationFmoc-Gln(Trt)-OH has good solubility properties in most organic solvents, and its use has been shown to result in significantly purer peptides than other derivatives used for the introduction of Gln [1]. Coupling can be performed by standard procedures. The trityl-protecting group is normally removed by 95% TFA in 1-3 hours, with no alkylation of Trp.

The product number for this product was previously 04-12-1090.

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References
Product Information
CAS number132327-80-1
Hill FormulaC₃₉H₃₄N₂O₅
Molar Mass610.72 g/mol
HS Code2924 29 99
Structure formula ImageStructure formula Image
Quality LevelMQ400
Applications
ApplicationFmoc-Gln(Trt)-OH Novabiochem®. CAS 132327-80-1, molar mass 610.72 g/mol.
Biological Information
Physicochemical Information
Melting Point130.5 °C
pH value5.4 (H₂O, 22.9 °C)
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -10°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to off white
Appearance of substance (visual)powder
Color index (0,5 M in DMF)≤ 160 Hazen
Identity (IR)passes test
Enantiomeric purity≥ 99.8 % (a/a)
Purity (HPLC)≥ 99.0 % (a/a)
Fmoc-ß-Ala-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-ß-Ala-Gln (Trt) -OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Gln(Trt)-Gln(Trt)-OH (HPLC)≤ 0.1 % (a/a)
Fmoc-Gln-OH (HPLC)≤ 0.1 % (a/a)
Assay free amino acid (GC)≤ 0.2 %
Purity (TLC(011A))≥ 98 %
Purity (TLC(0811))≥ 98 %
Solubility (25 mmole in 50 ml DMF)clearly soluble
Assay (acidimetric)≥ 93.0 %
Water (K. F.)≤ 2.0 %
Ethyl acetate (HS-GC)≤ 0.5 %
Acetate (IC)≤ 0.02 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Gln(Trt)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] P. Sieber, et al. (1991) Tetrahedron Lett., 32, 739.