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852077 Fmoc-Glu-ODmab

Fmoc-Glu-ODmab Novabiochem®. CAS 172611-75-5, molar mass 680.79 g/mol.

Fmoc-Glu-ODmab MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 172611-75-5 Molar Mass: 680.79 g/mol Hill Formula: C₄₀H₄₄N₂O₈
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
172611-75-5C₄₀H₄₄N₂O₈680.79 g/mol
Description
Catalogue Number852077
Replaces04-12-1174
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-L-glutamic acid α-4-{N-[1-(4,4-dimethyl-2,6-dioxocyclohexylidene)-3-methylbutyl]-amino} benzyl ester
Background InformationQuasi-orthogonally-protected Glu derivative.

The Dmab group can be removed selectively in the presence of tBu-based protecting groups by treatment with 2% hydrazine in DMF [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(ivDde) and Glu(ODmab) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.

The product number for this product was previously 04-12-1174.

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References
Product Information
CAS number172611-75-5
Hill FormulaC₄₀H₄₄N₂O₈
Molar Mass680.79 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Glu-ODmab Novabiochem®. CAS 172611-75-5, molar mass 680.79 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.5 % (a/a)
Purity (TLC(011A))≥ 90 %
Purity (TLC(0811))≥ 90 %
Assay (HPLC, area%)≥ 96.0 % (a/a)
For TLC-Systems see our General Catalog

Documentation

Fmoc-Glu-ODmab SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] W. C. Chan, et al. (1995) J. Chem. Soc., Chem. Commun., 2209.