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852095 Fmoc-Lys(Mca)-OH

Fmoc-Lys(Mca)-OH Novabiochem®. CAS 386213-32-7, molar mass 584.62 g/mol.

Fmoc-Lys(Mca)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 386213-32-7 Molar Mass: 584.62 g/mol Hill Formula: C₃₃H₃₂N₂O₈
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
386213-32-7C₃₃H₃₂N₂O₈584.62 g/mol
Description
Catalogue Number852095
Replaces04-12-1233
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-ε-7-methoxycoumarin-4-acetyl-L-lysine
Background InformationA modified lysine derivative for the preparation of fluorogenically-labeled peptides by Fmoc chemistry [1].

The Mca group fluoresces at 405 nm when stimulated at 340 nm, and is most commonly used in conjunction with Dabcyl and 2,4-dinitrophenyl quenching groups.

Recently, Fmoc-Lys(Mca)-OH has been used to prepare lanthanide-based luminescent proteins by native chemical ligation [2]. Lys(Mca) was found to be stable to HF cleavage conditions used to synthesize the thioester fragments needed for ligation.

The product number for this product was previously 04-12-1233.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number386213-32-7
Hill FormulaC₃₃H₃₂N₂O₈
Molar Mass584.62 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Lys(Mca)-OH Novabiochem®. CAS 386213-32-7, molar mass 584.62 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.0 % (a/a)
Purity (TLC(011A))≥ 97 %
Assay (HPLC, area%)≥ 97.0 % (a/a)
Water (K. F.)≤ 2.0 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Lys(Mca)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] J. L. Lauer-Fields, et al. (2001) Biochemistry, 40, 5795.
  • [1] C. F. W. Becker, et al. (2004) Bioconjugate Chem., 15, 1118.