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852094 Fmoc-Lys(Mmt)-OH

Fmoc-Lys(Mmt)-OH Novabiochem®. CAS 159857-60-0, molar mass 640.77 g/mol.

Fmoc-Lys(Mmt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 159857-60-0 Molar Mass: 640.77 g/mol Hill Formula: C₄₁H₄₀N₂O₅
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
159857-60-0C₄₁H₄₀N₂O₅640.77 g/mol
Description
Catalogue Number852094
Replaces04-12-1232
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-N-ε-4-methoxytrityl-L-lysine
Background InformationAn excellent derivative for the synthesis of branched peptides and peptides modified at the lysine side-chain [1], and for the construction of templates and multifunctionalized resins for combinatorial synthesis.

The side-chain Mmt group can be selectively removed in the same manner as Mtt with 1% TFA in DCM [2, 3, 4] or DCM/HFIP/TFE/TES (6.5:2:1:0.5) [5]. Alternatively, it can be removed under milder conditions with AcOH/TFE/DCM (1:2:7) [1], leaving Mtt intact.

The product number for this product was previously 04-12-1232.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number159857-60-0
Hill FormulaC₄₁H₄₀N₂O₅
Molar Mass640.77 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Lys(Mmt)-OH Novabiochem®. CAS 159857-60-0, molar mass 640.77 g/mol.
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 3 highly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.0 % (a/a)
Purity (TLC(0009))≥ 95 %
Assay (HPLC, area%)≥ 95.0 % (a/a)
Assay (acidimetric)≥ 80.0 %
Water (K. F.)≤ 2.0 %
For TLC-Systems see our General Catalog.
Product is stabilised with up to 20% diisopropylether upon drying.

Documentation

Fmoc-Lys(Mmt)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] S. Matysiak, et al. (1998) Tetrahedron Lett., 39, 1733.
  • [2] K. Barlos, et al., C. H. Schneider & A. N. Eberle (Eds), ESCOM, Leiden, 1993, pp. 283.
  • [3] A. Aletras, et al. (1995) Int. J. Peptide Protein Res., 45, 488.
  • [4] L. Bourel, et al. (2000) J. Peptide Sci., 6, 264.
  • [5] K. Barlos, personal communication.