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852066 Fmoc-Thr(Trt)-OH

Fmoc-Thr(Trt)-OH Novabiochem®. CAS 133180-01-5, molar mass 583.67 g/mol.

Fmoc-Thr(Trt)-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 133180-01-5 Molar Mass: 583.67 g/mol Hill Formula: C₃₈H₃₃NO₅
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
133180-01-5C₃₈H₃₃NO₅583.67 g/mol
Description
Catalogue Number852066
Replaces04-12-1141
Brand Family Novabiochem®
Alternate Names
  • N-α-Fmoc-O-trityl-L-threonine
Background InformationThe side-chain Trt group can be selectively removed with 1% TFA in DCM containing 5% TIS, enabling the side-chain hydroxyl group to be selectively modified whilst the derivative is attached to the solid support. This is an excellent derivative for the synthesis of phosphothreonine containing peptides and peptides modified at the threonine side-chain [1]. The use of trityl protected amino acids was shown to result in purer products than when standard t-Bu protected amino acids were utilized [2].

The product number for this product was previously 04-12-1141.

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References
Product Information
CAS number133180-01-5
Hill FormulaC₃₈H₃₃NO₅
Molar Mass583.67 g/mol
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
ApplicationFmoc-Thr(Trt)-OH Novabiochem®. CAS 133180-01-5, molar mass 583.67 g/mol.
Biological Information
Physicochemical Information
Melting Point70 - 85 °C
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 2 obviously hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at -15°C to -25°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to slight yellow to beige
Appearance of substance (visual)powder
Identity (IR)passes test
Enantiomeric purity≥ 99.0 % (a/a)
Purity (TLC(011A))≥ 98 %
Purity (TLC(0811))≥ 98 %
Assay (HPLC, area%)≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF)clearly soluble
Assay (acidimetric)≥ 78.0 %
Water (K. F.)≤ 1.5 %
For TLC-Systems see our General Catalog

Documentation

Fmoc-Thr(Trt)-OH SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] K. Barlos, et al. (1991) Tetrahedron Lett., 32, 471.
  • [2] K. Barlos, et al. (1998) J. Peptide Res., 51, 194.