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852287 Fmoc-p-Bz-Phe-OH

Fmoc-p-Bz-Phe-OH Fmoc-L-p-benzoylphenylalanine Novabiochem®. CAS 117666-96-3, molar mass 491.53 g/mol.

Fmoc-p-Bz-Phe-OH MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 117666-96-3 Molar Mass: 491.50 g/mol Hill Formula: C₃₁H₂₅NO₅
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Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
117666-96-3C₃₁H₂₅NO₅491.50 g/mol

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      Description
      Catalogue Number852287
      Brand Family Novabiochem®
      Alternate Names
      • (S)-3-(4-Benzoyl-phenyl)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-propionic acid,4-Benzoyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]phenylalanine
      Background InformationFmoc-p-Bz-Phe-OH-OH is a useful tool for preparing photoactivatable peptide-based affinity probes [1]. On photolysis at 366 nm, Benzoylphenylalanine (Bpa) generates a biradical that has a preference for insertion into C-H bonds, particularly those of Leu, Val and Met side chains.

      The derivative can be introduced using standard coupling method such as PyBOP and is stable to conditions used in peptide chain extension. For the cleavage of Bpa containing peptide from the resin, the use of thiols and silanes should be avoided as dithioketal formation and reduction, respectively, have been observed.
      References
      Product Information
      CAS number117666-96-3
      Hill FormulaC₃₁H₂₅NO₅
      Molar Mass491.50 g/mol
      HS Code2924 29 70
      Structure formula ImageStructure formula Image
      Quality LevelMQ200
      Applications
      ApplicationFmoc-p-Bz-Phe-OH Fmoc-L-p-benzoylphenylalanine Novabiochem®. CAS 117666-96-3, molar mass 491.53 g/mol.
      Biological Information
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Storage class10 - 13 Other liquids and solids
      WGKWGK 3 highly hazardous to water
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      StorageStore at +2°C to +8°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Colour (visual)white to slight yellow to beige
      Appearance of substance (visual)powder
      Identity (IR)passes test
      Optical rotation α 25/D (c=1 in DMF)-31.0 - -27.0 °
      Assay (HPLC, area%)≥ 98.0 % (a/a)
      Solubility (1 mmole in 2 ml DMF)clearly soluble
      Global Trade Item Number
      Catalogue Number GTIN
      8522870001 04027269194901

      Documentation

      Fmoc-p-Bz-Phe-OH SDS

      Title

      Safety Data Sheet (SDS) 

      Citations

      Title
      [1] K. T. O'Neil, et al. (1989) J. Biol. Chem., 264.