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371780 GP Antagonist-2A - Calbiochem

The GP Antagonist-2A controls the biological activity of GP. This small molecule/inhibitor is primarily used for Neuroscience applications.

GP Antagonist-2A - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: RPKPQQDWFDWDWM

Primary Target: Inhibits the activation of Gq by M1-muscarinic cholinergic receptors
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371780
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₇₉H₁₀₅N₂₁O₁₃S

Pricing & Availability

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371780-1MG
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      		 Plastic ampoule 1 mg
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      Description
      OverviewA peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.
      Catalogue Number371780
      Brand Family Calbiochem®
      SynonymsRPKPQQDWFDWDWM
      References
      ReferencesHunt, R.A., et al. 1999. Hypertension 34, 603.
      Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
      Mukai, H., et al. 1992. J. Biol. Chem. 267, 16237.
      Product Information
      ATP CompetitiveN
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₇₉H₁₀₅N₂₁O₁₃S
      Chemical formulaC₇₉H₁₀₅N₂₁O₁₃S
      ReversibleN
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetInhibits the activation of Gq by M1-muscarinic cholinergic receptors
      Purity≥95% by HPLC
      Physicochemical Information
      Cell permeableN
      Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      371780-1MG 04055977213409

      Documentation

      GP Antagonist-2A - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      GP Antagonist-2A - Calbiochem Certificates of Analysis

      TitleLot Number
      371780

      References

      Reference overview
      Hunt, R.A., et al. 1999. Hypertension 34, 603.
      Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
      Mukai, H., et al. 1992. J. Biol. Chem. 267, 16237.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision13-May-2010 JSW
      SynonymsRPKPQQDWFDWDWM
      DescriptionA peptide that selectively inhibits the activation of Gq by M1-muscarinic cholinergic receptors. Also inhibits activation by cholecystokinin receptor in pancreatic acini at 10 µM. Blocks angiotensin II-stimulated sis-inducing factor and STAT3 tyrosine phosphorylation.
      FormLyophilized solid
      FormulationSupplied as a trifluoroacetate salt.
      Chemical formulaC₇₉H₁₀₅N₂₁O₁₃S
      Peptide SequenceH-Arg-Pro-Lys-Pro-Gln-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH₂
      Purity≥95% by HPLC
      SolubilityH₂O (25 mg/ml)
      Storage -20°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
      Toxicity Standard Handling
      ReferencesHunt, R.A., et al. 1999. Hypertension 34, 603.
      Tsunoda Y., et al. 1995. Biochem. Biophys. Res. Commun. 211, 648.
      Mukai, H., et al. 1992. J. Biol. Chem. 267, 16237.