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361530 GSK-3β Substrate

GSK-3β Substrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: GPHRSTPESRAAV

361530
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      A part of the hydrophilic loop domain of presenilin 1 that is selectively recognized by GSK-3β. The sequence is not recognized by p38α, p38β, PKC, or Casein Kinase II. Undergoes phosphorylation at the Ser353 and Ser357 sites.
      Catalogue Number361530
      Brand Family Calbiochem®
      SynonymsGPHRSTPESRAAV
      References
      ReferencesKirschenbaum, F., et al. 2001. J. Biol. Chem. 276, 7366.
      Product Information
      FormWhite solid
      FormulationSupplied as an acetate salt.
      Hill FormulaC₅₆H₉₃N₂₁O₁₉
      Chemical formulaC₅₆H₉₃N₂₁O₁₉
      Hygroscopic Hygroscopic
      Applications
      Biological Information
      Purity≥95% by HPLC.
      Physicochemical Information
      Peptide SequenceH-Gly-Pro-His-Arg-Ser-Thr-Pro-Glu-Ser-Arg-Ala-Ala-Val-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      361530 0

      Documentation

      GSK-3β Substrate Certificates of Analysis

      TitleLot Number
      361530

      References

      Reference overview
      Kirschenbaum, F., et al. 2001. J. Biol. Chem. 276, 7366.

      Brochure

      Title
      Alzheimer's Disease Brochure & Technical Guide
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision30-October-2009 RFH
      SynonymsGPHRSTPESRAAV
      DescriptionA part of the hydrophilic loop domain of presenilin 1 that is selectively recognized by GSK-3β. The sequence is not recognized by p38α, p38β, PKC, and CK II. Undergoes phosphorylation at the Ser353 and Ser357 sites. Incorporation of radiolabeled phosphate can be determined by adsorption of the peptide to P81 membranes and scintillation counting.
      FormWhite solid
      FormulationSupplied as an acetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₅₆H₉₃N₂₁O₁₉
      Peptide SequenceH-Gly-Pro-His-Arg-Ser-Thr-Pro-Glu-Ser-Arg-Ala-Ala-Val-OH
      Purity≥95% by HPLC.
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesKirschenbaum, F., et al. 2001. J. Biol. Chem. 276, 7366.