Millipore Sigma Vibrant Logo

361561 GSK-3 Substrate

GSK-3 Substrate MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: PGS-1 Peptide

361561
  
Retrieving price...
Price could not be retrieved
Minimum Quantity is a multiple of
Maximum Quantity is
Upon Order Completion More Information
You Saved ()
 
—
Request Pricing
—
Limited Availability Limited Availability
In Stock 
Discontinued
Limited Quantities Available
Availability to be confirmed
    Remaining : Will advise
      Remaining : Will advise
      Will advise
      Contact Customer Service
      Contact Customer Service

       

      Contact Customer Service

      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      A synthetic peptide that can be used as an excellent substrate for glycogen synthase kinase-3α/β (GSK-3α/β) in in vitro kinase assays. The peptide sequence is derived from human muscle glycogen synthase 1 (amino acids 636-661).
      Catalogue Number361561
      Brand Family Calbiochem®
      SynonymsPGS-1 Peptide
      References
      ReferencesIlouz, R., et al. 2006.J. Biol. Chem. 281, 30621. Sutherland, C., et al. 1993. Biochem. J. 296, 15.
      Product Information
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Hill FormulaC₁₂₃H₁₉₁N₄₀O₄₈P
      Chemical formulaC₁₂₃H₁₉₁N₄₀O₄₈P
      Hygroscopic Hygroscopic
      Applications
      Application CommentsReconstitute 1 mg of the substrate in 1.3 ml DI water resulting in a 250 µM solution recommended for GSK-3 assays
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Peptide SequenceH-Tyr-Arg-Arg-Ala-Ala-Val-Pro-Pro-Ser-Pro-Ser-Leu-Ser-Arg-His-Ser-Ser-Pro-His-Gln-pSer-Glu-Asp-Glu-Glu-Glu-OH
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Blue Ice Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      361561 0

      Documentation

      GSK-3 Substrate Certificates of Analysis

      TitleLot Number
      361561

      References

      Reference overview
      Ilouz, R., et al. 2006.J. Biol. Chem. 281, 30621. Sutherland, C., et al. 1993. Biochem. J. 296, 15.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision28-April-2009 RFH
      SynonymsPGS-1 Peptide
      DescriptionA synthetic peptide that contains the glycogen synthase kinase-3 (GSK-3) recognition motif S-X-X-X-S(p) and serves as an excellent GSK-3α/β substrate in in vitro kinase assays. The peptide sequence is derived from the highly conserved GSK phosphorylation site in glycogen synthase 1 of multiple species, including human, mouse, rat, dog, cow, pig, rabbit, and horse. The totally non-phosphorylated peptide cannot be recognized by and is therefore not a substrate for GSK-3.
      FormLyophilized
      FormulationSupplied as a trifluoroacetate salt.
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₂₃H₁₉₁N₄₀O₄₈P
      Peptide SequenceH-Tyr-Arg-Arg-Ala-Ala-Val-Pro-Pro-Ser-Pro-Ser-Leu-Ser-Arg-His-Ser-Ser-Pro-His-Gln-pSer-Glu-Asp-Glu-Glu-Glu-OH
      Purity≥95% by HPLC
      SolubilityH₂O (1 mg/ml)
      CommentsReconstitute 1 mg of the substrate in 1.3 ml DI water resulting in a 250 µM solution recommended for GSK-3 assays
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesIlouz, R., et al. 2006.J. Biol. Chem. 281, 30621. Sutherland, C., et al. 1993. Biochem. J. 296, 15.