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368068 Granzyme B Substrate IX, Fluorogenic

368068
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.





      A fluorogenic substrate for granzyme B (kcat/Km = 3,330 M-1s-1) that also recognizes granzyme B variants (kcat/Km = 55 M-1s-1 for R192A and kcat/Km = 8.8 M-1s-1 for R192E).
      Catalogue Number368068
      Brand Family Calbiochem®
      SynonymsAc-IEPD-AMC
      References
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.
      Product Information
      FormLyophilized
      Hill FormulaC₃₂H₄₁N₅O₁₁
      Chemical formulaC₃₂H₄₁N₅O₁₁
      Applications
      Biological Information
      Purity≥95% by HPLC
      Physicochemical Information
      Emission max.
      Excitation max.
      Peptide SequenceAc-Ile-Glu-Pro-Asp-AMC
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Granzyme B Substrate IX, Fluorogenic Certificates of Analysis

      TitleLot Number
      368068

      References

      Reference overview
      Harris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-July-2008 RFH
      SynonymsAc-IEPD-AMC
      DescriptionA fluorogenic substrate for granzyme B (kcat/Km = 3,330 M-1s-1) that also recognizes granzyme B variants (kcat/Km = 55 M-1s-1 for R192A and kcat/Km = 8.8 M-1s-1 for R192E).
      FormLyophilized
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₃₂H₄₁N₅O₁₁
      Peptide SequenceAc-Ile-Glu-Pro-Asp-AMC
      Purity≥95% by HPLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Protect from light
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesHarris, J.L., et al. 1998. J. Biol. Chem. 273, 27364.
      Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.