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370664 Guanosine 3ʹ,5ʹ-cyclic Monophosphate, β-Phenyl-1,N²-etheno-8-bromo-, Sodium Salt

A potent cell-permeable activator of protein kinase G type 1α and 1β.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: 8-Br-PET-cGMP, Na

Primary Target: Protein kinase G type 1α and 1β
370664
  
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      Overview

      Replacement Information

      Key Spec Table

      CAS #Empirical Formula
      144510-04-3C₁₈H₁₄BrN₅O₇P · Na
      Description
      Overview

      This product has been discontinued.





      A potent cell-permeable activator of protein kinase G type 1α and 1β. Reported to be one of the best known activators of PKG isozyme 1β. Also acts as an excellent muscle relaxant. Note: 10 µmol = 5.46 mg.
      Catalogue Number370664
      Brand Family Calbiochem®
      Synonyms8-Br-PET-cGMP, Na
      References
      ReferencesVaandrager, A.B., et al. 1997. J. Biol. Chem. 272, 11816.
      Sekhar, K.R., et al. 1992. Mol. Pharmacol. 42, 103.
      Product Information
      CAS number144510-04-3
      ATP CompetitiveN
      FormLyophilized
      Hill FormulaC₁₈H₁₄BrN₅O₇P · Na
      Chemical formulaC₁₈H₁₄BrN₅O₇P · Na
      Hygroscopic Hygroscopic
      ReversibleN
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Primary TargetProtein kinase G type 1α and 1β
      Purity≥98% by HPLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Hygroscopic Hygroscopic
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      370664 0

      Documentation

      References

      Reference overview
      Vaandrager, A.B., et al. 1997. J. Biol. Chem. 272, 11816.
      Sekhar, K.R., et al. 1992. Mol. Pharmacol. 42, 103.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision07-July-2008 RFH
      Synonyms8-Br-PET-cGMP, Na
      DescriptionA potent and cell-permeable activator of protein kinase G type Iα and Iβ. Reported to be one of the best activators of PKG isozyme Iβ. Also acts as an excellent muscle relaxant. Note: 10 µmol = 5.46 mg.
      FormLyophilized
      CAS number144510-04-3
      Chemical formulaC₁₈H₁₄BrN₅O₇P · Na
      Structure formulaStructure formula
      Purity≥98% by HPLC
      SolubilityH₂O (1 mg/ml)
      Storage -20°C
      Hygroscopic
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
      Toxicity Standard Handling
      ReferencesVaandrager, A.B., et al. 1997. J. Biol. Chem. 272, 11816.
      Sekhar, K.R., et al. 1992. Mol. Pharmacol. 42, 103.