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851013 HATU

HATU Novabiochem®. CAS 148893-10-1, molar mass 380.23 g/mol.

HATU MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
CAS #: 148893-10-1 Molar Mass: 380.23 g/mol Hill Formula: C₁₀H₁₅N₆O * F₆P
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Overview

Replacement Information

Key Spec Table

CAS #Hill FormulaMolar Mass
148893-10-1C₁₀H₁₅N₆O * F₆P380.23 g/mol
Description
Catalogue Number851013
Replaces01-62-0041
Brand Family Novabiochem®
Background InformationA highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

The product number for this product was previously 01-62-0041.

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References
Product Information
CAS number148893-10-1
Hill FormulaC₁₀H₁₅N₆O * F₆P
Molar Mass380.23 g/mol
HS Code2933 99 99
Structure formula ImageStructure formula Image
Quality LevelMQ300
Applications
ApplicationHATU Novabiochem®. CAS 148893-10-1, molar mass 380.23 g/mol.
Biological Information
Physicochemical Information
Melting Point186 °C decomposes
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Hazard Pictogram(s) Hazard Pictogram(s)
Hazard Statement(s)H317: May cause an allergic skin reaction.
H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled.
EUH044: Risk of explosion if heated under confinement.
Precautionary Statement(s)P261: Avoid breathing dust.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves.
P284: Wear respiratory protection.
P302 + P352: IF ON SKIN: Wash with plenty of water.
P333 + P313: If skin irritation or rash occurs: Get medical advice/ attention.
Signal WordDanger
Storage class4.1B Flammable solid hazardous materials
WGKWGK 3 highly hazardous to water
Safety Information
Categories of dangersensitizing
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Declaration (railroad and road) ADR, RIDUN 1325 , 4.1, II
Declaration (transport by air) IATA-DGRUN 1325 , 4.1, II
Declaration (transport by sea) IMDG-CodeUN 1325 , 4.1, II
Supplemental Information
Specifications

Documentation

HATU SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
  • [1] L. A. Carpino (1993) J. Am. Chem. Soc., 115, 4397.
  • [2] F. Albericio, et al. (1998) J. Org. Chem., 63, 9678.
  • [3] J. A. Carpino, et al., in "Innovation & Perspectives in Solid Phase Synthesis, 3rd International Symposium", R. Epton (Ed.), Mayflower Worldwide Ltd., 1994, pp. 95.