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855070 HMBA-PEGA resin

Overview

Replacement Information

Key Spec Table

CAS #
58318-77-7
Description
Catalogue Number855070
Replaces01-64-0113
Brand Family Novabiochem®
Alternate Names
  • 4-Hydroxymethylbenzoic acid PEGA resin
Background InformationThis support consists of amino PEGA resin derivatized with Sheppard's base-labile 4-hydroxymethylbenzoic acid linker [1].

For further information, please refer to the product entry for amino PEGA resin (855015).Note: PEGA resins are supplied swollen in ethanol, with 1g dry resin corresponding to approximately 15 mL of swollen resin. As the beads of PEGA resins become very sticky and easily damaged when shrunk or dried, they are best handled in a swollen state. To use, the appropriate amount of swollen resin should be weighed into a reaction vessel and any residual ethanol removed by copious washings with the appropriate solvent or solvent mixture. After peptide assembly, the resin should be washed with DCM and transferred to the cleavage vessel. Excess DCM can be removed under vacuum, and the shrunk resin treated with the TFA cocktail.

The characteristics of the swollen resin, its robustness and high permeability enables its use in both batch and continuous flow synthesis apparatus.

The product number for this product was previously 01-64-0113.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
References
Product Information
CAS number58318-77-7
HS Code3907 29 90
Structure formula ImageStructure formula Image
Quality LevelMQ200
Applications
Biological Information
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Storage class10 - 13 Other liquids and solids
WGKWGK 1 slightly hazardous to water
Safety Information
Product Usage Statements
Storage and Shipping Information
StorageStore at +2°C to +8°C.
Packaging Information
Transport Information
Supplemental Information
Specifications
Color (visual)white to yellow to beige
Appearance of substance (visual)beads
Loading (determined from the substitution of the Fmoc-Leu loaded resin)0.20 - 0.50 mmol/g
Swelling Volume (in DMF)lot specific result
dry resin %lot specific result
The resin is sold swollen in ethanol.

Documentation

HMBA-PEGA resin SDS

Title

Safety Data Sheet (SDS) 

Citations

Title
[1] R. C. Sheppard, et al. (1982) Int. J. Peptide Protein Res., 20, 451.