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385874 Hsp47 Inhibitor

Hsp47 Inhibitor MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
385874
  
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      Overview

      Replacement Information
      Description
      Overview

      This product has been discontinued.

      We apologize for the inconvenience, but we do not currently have an alternative product.





      A thioether compound that inhibits collagen-specific Hsp47-induced collagen chaperone activity in an in vitro fibril formation assay (IC50 = 6.3 µM in phosphate buffer pH 7.4 at 34°C, 800 nM collagen, and 1.2 µM Hsp47).
      Catalogue Number385874
      Brand Family Calbiochem®
      References
      ReferencesThomson, C.A., et al. 2005. J. Med. Chem. 48, 1680.
      Product Information
      FormYellow solid
      Hill FormulaC₁₈H₁₂ClN₃O₂S₂ • 1.5 H₂O
      Chemical formulaC₁₈H₁₂ClN₃O₂S₂ • 1.5 H₂O
      Structure formula ImageStructure formula Image
      Applications
      Biological Information
      Purity≥98% by HPLC (sum of two isomers)
      Physicochemical Information
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Protect from Light Protect from light
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Packaged under inert gas Packaged under inert gas
      Transport Information
      Supplemental Information
      Specifications
      Global Trade Item Number
      Catalogue Number GTIN
      385874 0

      Documentation

      References

      Reference overview
      Thomson, C.A., et al. 2005. J. Med. Chem. 48, 1680.

      Citations

      Title
      Kaiser W et al. 2009. J. Proteome Res. 8, 2903.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision14-July-2008 RFH
      DescriptionA thioether compound that inhibits collagen-specific Hsp47-induced collagen chaperone activity in an in vitro fibril formation assay (IC50 = 6.3 µM in phosphate buffer pH 7.4 at 34°C, 800 nM collagen, and 1.2 µM Hsp47).
      FormYellow solid
      Intert gas (Yes/No) Packaged under inert gas
      Chemical formulaC₁₈H₁₂ClN₃O₂S₂ • 1.5 H₂O
      Structure formulaStructure formula
      Purity≥98% by HPLC (sum of two isomers)
      SolubilityDMSO (5 mg/ml)
      Storage Protect from light
      +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesThomson, C.A., et al. 2005. J. Med. Chem. 48, 1680.
      CitationKaiser W et al. 2009. J. Proteome Res. 8, 2903.